摘要/Abstract

α-酮酸作为一种羧酸, 可以通过脱羧作用, 作为酰基化试剂应用于有机合成, 但是传统方法往往依赖过渡金属催化剂或高温等反应条件, 在一定程度上限制了其应用. 近年来发展的可见光诱导的有机反应由于条件温和及易于操作等优点而受到广泛关注. 综述了无金属条件下可见光诱导的α-酮酸的相关反应研究进展, 主要包括在酰基化反应和环化反应中的应用.
关键词: α-酮酸, 可见光, 无金属催化, 酰基化
As a carboxylic acid, α-keto acid can be used as an acylating reagent by decarboxylation in organic synthesis. However, traditional methods often need transition metal catalysts or high temperatures, which limits the application of α-keto acid to a certain extent. In recent years, organic transformations induced by visible light have attracted extensive attention due to its mild conditions and simple operations. Herein, the recent advances of metal-free photocatalytic application of α-keto acids are summarized, which mainly include acylation reactions and cyclization reactions.
Key words: α-keto acid, visible light, metal-free catalysis, acylation


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