摘要/Abstract

报道了一种三甲基溴硅烷促进的通过碳-碳键交叉偶联反应合成N-甲基吲哚二聚体的方法. 在温和条件下以最高95%的收率方便地合成了一系列2,3′-吲哚基二氢吲哚类化合物. 克级反应证明了该方法的实用性. 初步研究了目标产物的紫外-可见吸收和荧光光谱性质.
关键词: 吲哚, 二聚, 交叉偶联, 吲哚基二氢吲哚
A dimerization of N-methylindoles by trimethylsilyl bromide promoted C—C bond cross coupling reactions is described. A series of 2,3'-linked indolylindolines are smoothly installed under mild reaction conditions with up to 95% yields. The gram scale reactions demonstrate the practicality of this protocol. The UV-vis absorption and fluorescence spectra properties of target products are preliminarily studied.
Key words: indole, dimerization, cross-coupling, indolylindoline


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