摘要/Abstract

芳基和砜基化合物在合成化学、药物化学、材料化学等领域具有广泛的应用价值. 因此, 其清洁、高效的构建方法备受人们的关注. 芳基偶氮砜在光、电或热条件下可以发生C—N和S—N键均裂, 产生芳基和砜基自由基, 进而发生芳基化或砜基化反应选择性构建芳基或砜基化合物. 归纳总结了近年来芳基偶氮砜参与的芳基化及砜基化反应最新研究进展, 重点介绍了其合成方法及反应机理, 并对该领域的未来发展进行了展望.
关键词: 芳基偶氮砜, 光催化, 电催化, 芳基化, 砜基化
Aromatic ring- and sulfone-containing compounds are widely used in the fields of synthetic chemistry, medicinal chemistry and material chemistry. Therefore, it is of great significance to develop a simple, green and efficient method to construct aryl and sulfonyl compounds. Arylazo sulfones can be used as arylation or sulfonylation reagents to access aryl and sulfonyl compounds via hemolytic cleavage of C—N and N—S bonds to generate aryl radical and sulfonyl radical. In this review, the recent research progress of arylations and sulfonylations using arylazo sulfones is summarized. The synthetic methods and the related reaction mechanisms are highlighted, and an outlook of this research field is also given.
Key words: arylazo sulfones, photocatalysis, electrocatalytic, arylations, sulfonylations


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