摘要/Abstract

发展了一例空气氛围下氧气作为无污染氧化剂合成α-酮酯的方法. 以易得的α-重氮酯为起始原料, 该转化在采用曙红Y作为光敏剂的光诱导条件下进行. 反应在室温和空气氛围下操作, 底物兼容性好. 提供了一个绿色、简便合成结构多样的α-酮酯的方法.
关键词: 光催化, 无过渡金属, 空气氧化, α-重氮酯, α-酮酯
Herein, an aerobic oxidation approach for the synthesis of α-keto esters using oxygen as a cheap and pollution-free oxidant has been developed. By using readily available α-diazo esters as starting materials, the transformation was achieved by the inducement of visible light with eosin Y as the light sensitizer. The reactions proceed at room temperature under air atmosphere, tolerating substrates with broad scope, thus providing a green and facile synthetic approach to structurally diverse α-keto esters.
Key words: photocatalysis, transition metal-free, aerobic oxidation, α-diazo esters, α-keto esters


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