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颈椎前路三节段融合与置换混合术的力学特性

清华大学 辅仁网/2017-07-07

颈椎前路三节段融合与置换混合术的力学特性
刘伟强1,2(),吕聪伟1,3,蒲婷3,颜滨4,廖振华2
2. 深圳清华大学研究院, 深圳 518057
3. 清华大学 深圳研究生院, 深圳 518055
4. 深圳市第二人民医院, 深圳 518049
Biomechanical characteristics of a three-level cervical disc hybrid construct: An in vitro investigation
Weiqiang LIU1,2(),Congwei LV1,3,Ting PU3,Bin YAN4,Zhenhua LIAO2
1. Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China
2. Research Institute of Tsinghua University in Shenzhen, Shenzhen 518057, China
3. Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China
4. Shenzhen No.2 People's Hospital Shenzhen, Shenzhen 518049, China

摘要:
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摘要为研究人体颈椎三节段混合手术后手术节段与相邻节段的运动规律,对7具人体颈椎标本先实施C4-C5前路人工椎间盘置换,再实施C3-C4和C5-C6两节段椎间盘切除术后颈前路植骨融合固定,利用材料力学试验机和非接触式光学测量系统测量各节段的运动信息,比较三节段混合组与完整组、单节段置换组的体外生物力学特性,分析三节段混合术与课题组前期三节段融合术(限制型、滑动型)运动保留能力。结果表明: 三节段混合术保留生理活动度能力明显优于三节段融合术(无论限制型或滑动型固定板)。

关键词 人工颈椎间盘,颈椎前路融合板,生物力学,混合手术
Abstract:This article describes the rules of motion of a human cervical disc after a 3-level hybrid construct. 7 cadaveric cervical spines (C2-T1) were initially tested in intact condition. Then, all patients had a 1-level (C4-C5) total disc replacement (TDR) followed by a 2-level (C3-C4 and C5-C6 segments) anterior cervical discectomy and fusion (ACDF). The movement differences among the 3-level hybrid construct, the intact disc and the 1-level TDR were compared with the 3-level hybrid construct and previous 3-level fusion data (dynamic and static plating systems). The comparisons show that the 3-level hybrid construct performs better than 3-level fusion.

Key wordsartificial cervical intervertebral discanterior cervical platebiomechanicshybrid construct
收稿日期: 2013-01-29 出版日期: 2015-09-03
ZTFLH: 
基金资助:“十二五”国家科技支撑计划资助项目 (2012BA118B05)
引用本文:
刘伟强, 吕聪伟, 蒲婷, 颜滨, 廖振华. 颈椎前路三节段融合与置换混合术的力学特性[J]. 清华大学学报(自然科学版), 2014, 54(5): 685-689.
Weiqiang LIU, Congwei LV, Ting PU, Bin YAN, Zhenhua LIAO. Biomechanical characteristics of a three-level cervical disc hybrid construct: An in vitro investigation. Journal of Tsinghua University(Science and Technology), 2014, 54(5): 685-689.
链接本文:
http://jst.tsinghuajournals.com/CN/ http://jst.tsinghuajournals.com/CN/Y2014/V54/I5/685


图表:
标本术后效果
试验台
各种工况下各节段运动分布
猪颈椎标本三节段融合
颈椎节段 Flex工况
3-Hybrid/% 滑动型/% 限制型/%
C2-C3 24.73 245.37 43.14
C3-C6 -17.98 -49.31 -69.53
C6-C7 21.53 19.77 58.45
C7-T1 65.26 160.08 183.33


Flex工况术后手术节段及相邻节段运动变化幅度
颈椎节段 Ext工况
3-Hybrid/% 滑动型/% 限制型/%
C2-C3 2.57 42.28 23.46
C3-C6 -17.92 -35.45 -46.47
C6-C7 39.17 32.32 14.91
C7-T1 57.24 4.72 55.09


Ext工况术后手术节段及相邻节段运动变化幅度


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[1]刘伟强, 蒲婷, 顾洪生, 廖振华, 姜锦鹏. 中国人颈椎间盘尺寸分析[J]. 清华大学学报(自然科学版), 2014, 54(2): 172-177.

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