) 济南大学教育与心理科学学院, 济南 250022
收稿日期:2018-11-26出版日期:2019-10-15发布日期:2019-08-19通讯作者:陈功香E-mail:sep_chengx@ujn.edu.cn基金资助:* 国家社科基金一般项目资助(18BGL123)Anxiety in individuals with Autism Spectrum Disorders: Mechanism, assessment and treatment
LIU Chunyan, CHEN Gongxiang() School of Education and Psychology, University of Jinan, Jinan 250022, China
Received:2018-11-26Online:2019-10-15Published:2019-08-19Contact:CHEN Gongxiang E-mail:sep_chengx@ujn.edu.cn摘要/Abstract
摘要： 自闭症谱系障碍是一种神经发育性障碍, 主要表现为社会交往互动障碍和重复刻板性行为。焦虑或焦虑障碍常被认为是自闭症个体最普遍的共病之一。焦虑与自闭症之间的关系尚不明确, 自闭症个体的焦虑与无法忍受不确定性、杏仁核功能和体积、情绪调节策略、消极思维存在一定关联; 目前已经开发出专门用于自闭症个体焦虑的评估工具; 修订版认知行为疗法对自闭症个体焦虑的治疗取得了良好效果。未来的研究应着重探索自闭症个体焦虑的认知与神经机制, 检验专用评估工具的有效性, 继续关注现代技术(如虚拟现实技术)对自闭症个体焦虑的治疗效果。
参考文献 80
| [1] | 古若雷, 罗跃嘉 . ( 2008). 焦虑情绪对决策的影响. 心理科学进展, 16( 4), 518-523. |
| [2] | 刘泱慧, 位照国, 刘铁榜 . ( 2014). 无法忍受不确定性的起源、发展及研究. 中国心理卫生杂志, 28( 10), 796-800. |
| [3] | 彭家欣, 杨奇伟, 罗跃嘉 . ( 2013). 不同特质焦虑水平的选择性注意偏向. 心理学报, 45( 10), 1085-1093. |
| [4] | 彭子文, 刘静溪, 韦臻, 梁晶晶 . ( 2017). 自闭症与“社会脑”: 功能影像的发现. 华南师范大学学报(社会科学版), 49( 6), 82-88. |
| [5] | 李志勇, 王大鹏, 吴明证, 欧阳儒阳, 沈丹琦 . ( 2015). 无法忍受不确定性与担忧、焦虑的关系: 问题取向的中介作用. 中国临床心理学杂志, 23( 5), 808-811. |
| [6] | 陈巍, 安龙, 丁峻, 袁逖飞 . ( 2010). 自闭症脑功能性关联障碍研究进展: 来自fMRI的证据. 中国特殊教育, 120( 6), 54-58. |
| [7] | Aldao A., Nolen-Hoeksema S., & Schweizer S . ( 2010). Emotion-regulation strategies across psychopathology: A meta-analytic review. Clinical Psychology Review, 30( 2), 217-237. |
| [8] | American Psychiatric Association. ( 2000). Diagnostic and statistical manual of mental disorders (DSM-IV-TR). Arlington: American Psychiatric Publishing. |
| [9] | American Psychiatric Association. ( 2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington: American Psychiatric Publishing. |
| [10] | Andrew T. H., Amanda L. R., & Mirko U . ( 2018). Exploring the nature of anxiety in young adults on the autism spectrum: A qualitative study. Research in Autism Spectrum Disorders, 55( 11), 25-37. |
| [11] | Attwood, T. ( 2006). Asperger’s syndrome and problems related to stress. In Baron, M. G., Groden, J., Groden, G., & Lipsitt, L. P. (Eds.), Stress and coping in autism (pp. 351-370). New York: Oxford University Press. |
| [12] | Bellini, S. ( 2004). Social skill deficits and anxiety in high-functioning adolescents with autism spectrum disorders. Focus on Autism & Other Developmental Disabilities, 19( 2), 78-86. |
| [13] | Boulter C., Freeston M., South M., & Rodgers J . ( 2014). Intolerance of uncertainty as a framework for understanding anxiety in children and adolescents with autism spectrum disorders. Journal of Autism & Developmental Disorders, 44( 6), 1391-1402. |
| [14] | Bruggink A., Huisman S., Vuijk R., Kraaij V., & Garnefski N . ( 2016). Cognitive emotion regulation, anxiety and depression in adults with autism spectrum disorder. Research in Autism Spectrum Disorders, 22, 34-44. |
| [15] | Cachia R. L., Anderson A., & Moore D. W . ( 2016). Mindfulness in individuals with autism spectrum disorder: A systematic review and narrative analysis. Journal of Autism & Developmental Disorders, 3( 2), 165-178. |
| [16] | Cai R. Y., Richdale A. L., Dissanayake C., & Uljarević M . ( 2018). Brief report: Inter-relationship between emotion regulation, intolerance of uncertainty, anxiety, and depression in youth with autism spectrum disorder. Journal of Autism & Developmental Disorders, 48( 1), 316-325. |
| [17] | Cameron K., Ogrodniczuk J., & Hadjipavlou G . ( 2014). Changes in alexithymia following psychological intervention: A review. Harvard Review of Psychiatry, 22( 3), 162-78. |
| [18] | Carleton R. N . ( 2012). The intolerance of uncertainty construct in the context of anxiety disorders: Theoretical and practical perspectives. Expert Review of Neurotherapeutics, 12( 8), 937-947. |
| [19] | Chung K-M., & Jung D. ( 2017). Validity and reliability of the Korean version of autism spectrum disorders-comorbid for children (asd-cc). Research in Autism Spectrum Disorders, 39, 1-10. |
| [20] | Davis S., Shisca D., & Howell P . ( 2007). Anxiety in speakers who persist and recover from stuttering. Journal of Communication Disorders, 40( 5), 398-417. |
| [21] | Drmic I. E., Aljunied M., & Reaven J . ( 2017). Feasibility, acceptability and preliminary treatment outcomes in a school-based cbt intervention program for adolescents with asd and anxiety in singapore. Journal of Autism & Developmental Disorders, 47( 12), 3909-3929. |
| [22] | Farrugia S., & Hudson J. ( 2006). Anxiety in adolescents with asperger syndrome: Negative thoughts, behavioral problems, and life interference. Focus on Autism & Other Developmental Disabilities, 21( 1), 25-35. |
| [23] | Glod M., Creswell C., Waite P., Jamieson R., Mcconachie H., South M. D., & Rodgers J . ( 2017). Comparisons of the factor structure and measurement invariance of the spence children's anxiety scale-parent version in children with autism spectrum disorder and typically developing anxious children. Journal of Autism & Developmental Disorders, 47( 12), 3834-3846. |
| [24] | Groden J., Baron M. G., & Groden, G .( 2006) . Assessment and coping strategies. In Baron, M. G., Groden, J., Groden, G., & Lipsitt, L. P. (Eds.), Stress and coping in autism (pp. 15-41). New York: Oxford University Press. |
| [25] | Groden J., Diller A., Bausman M., Velicer W., Norman G., & Cautela J . ( 2001). The development of a stress survey schedule for persons with autism and other developmental disabilities. Journal of Autism & Developmental Disorders, 31( 2), 207-217. |
| [26] | Herrington J. D., Maddox B. B., Kerns C. M., Rump K., Worley J. A., Bush J. C., … Miller J. S . ( 2017). Amygdala volume differences in autism spectrum disorder are related to anxiety. Journal of Autism & Developmental Disorders, 47( 12), 3682-3691. |
| [27] | Herrington J. D., Maddox B. B., Mcvey A. J., Franklin M. E., Yerys B. E., Miller J. S., & Schultz R. T . ( 2017). Negative valence in autism spectrum disorder: The relationship between amygdala activity, selective attention, and co-occurring anxiety. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2( 6), 510-517. |
| [28] | Herrington J. D., Miller J. S., Pandey J., & Schultz R. T . ( 2016). Anxiety and social deficits have distinct relationships with amygdala function in autism spectrum disorder. Social Cognitive & Affective Neuroscience, 11( 6), 907-914. |
| [29] | Jitlina K., Zumbo B., Mirenda P., Ford L., Bennett T., Georgiades S., … Elsabbagh M . ( 2017). Psychometric properties of the spence children's anxiety scale: Parent report in children with autism spectrum disorder. Journal of Autism & Developmental Disorders, 47( 12), 3847-3856. |
| [30] | Johnco C., & Storch, E. A. ( 2015). Anxiety in youth with autism spectrum disorders: Implications for treatment. Expert Review of Neurotherapeutics, 15( 11), 1343-1352. |
| [31] | Keefer A., Kreiser N. L., Singh V., Blakeley-Smith A., Duncan A., Johnson C., .. Vasa R. A . ( 2016). Intolerance of uncertainty predicts anxiety outcomes following cbt in youth with asd. Journal of Autism & Developmental Disorders, 47( 12), 3949-3958. |
| [32] | Keefer A., Kreiser N. L., Singh V., Blakeley-Smith, A., Reaven, J., & Vasa, R. A .( Accepted/In press). Exploring relationships between negative cognitions and anxiety symptoms in youth with autism spectrum disorder. Behavior Therapy, 49 2017. 12. 002 |
| [33] | Kerns C. M., & Kendall, P. C. ( 2013). The presentation and classification of anxiety in autism spectrum disorder. Clinical Psychology Science & Practice, 19( 4), 323-347. |
| [34] | Kerns C. M., Kendall P. C., Berry L., Souders M. C., Franklin M. E., Schultz R. T., … Herrington J . ( 2014). Traditional and atypical presentations of anxiety in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44( 11), 2851-2861. |
| [35] | Kerns C. M., Renno P., Kendall P. C., Wood J. J., & Storch E. A . ( 2016). Anxiety disorders interview schedule-autism addendum: Reliability and validity in children with autism spectrum disorder. Journal of Clinical Child & Adolescent Psychology, 46( 1), 88-100. |
| [36] | Kester K. R., & Lucyshyn, J. M. ( 2018). Cognitive behavior therapy to treat anxiety among children with autism spectrum disorders: A systematic review. Research in Autism Spectrum Disorders, 52, 37-50. |
| [37] | Kim J. A., Szatmari P., Bryson S. E., Streiner D. L., & Wilson F. J . ( 2000). The prevalence of anxiety and mood problems among children with autism and asperger syndrome. Autism, 4( 2), 117-132. |
| [38] | Kleinhans N. M., Richards T., Weaver K., Johnson L. C., Greenson J., Dawson G., .. Aylward E .( 2010). Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders. Neuropsychologia, 48( 12), 3665-3670. |
| [39] | Lecavalier L., Wood J. J., Halladay A. K., Jones N. E., Aman M. G., Cook E. H., .. Scahill L . ( 2014). Measuring anxiety as a treatment endpoint in youth with autism spectrum disorder. Journal of Autism & Developmental Disorders, 44( 5), 1128-1143. |
| [40] | Lei J., Sukhodolsky D. G., Abdullahi S. M., Braconnier M. L., Kautz C. C., Pelphrey K. A., & Ventola P. E .( 2017). Characterising the relationship between anxiety, executive function, and restricted and repetitive behaviours in children and adolescents with autism spectrum disorder. Retrieved October 3, 2018, from |
| [41] | Leyfer O. T., Folstein S. E., Bacalman S., Davis N., Dinh E., Morgan J., .. Lainhart J. E . ( 2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849-861. |
| [42] | Lugo-Marína J., Magán-Maganto M., Rivero-Santana A., Cuellar-Pompa L., Alviani M., Jenaro-Rio C., .. Canal-Bedia R . ( 2019) Prevalence of psychiatric disorders in adults with autism spectrum disorder: A systematic review and meta-analysis. Research in Autism Spectrum Disorders, 59, 22-33. |
| [43] | MacNeil B. M., Lopes V. A., & Minnes P. M . ( 2009). Anxiety in children and adolescents with autism spectrum disorders. Research in Autism Spectrum Disorders, 3( 1), 1-21. |
| [44] | Magiati I., Chan J. Y., Tan W. L. J., & Poon K. K . ( 2014). Do non-referred young people with autism spectrum disorders and their caregivers agree when reporting anxiety symptoms? A preliminary investigation using the spence children's anxiety scale. Research in Autism Spectrum Disorders, 8( 5), 546-558. |
| [45] | Magiati I., Lerh J. W., Hollocks M. J., Uljarevic M., Rodgers J., Mcconachie H., .. Simonoff E . ( 2017). The measurement properties of the spence children's anxiety scale-parent version in a large international pooled sample of young people with autism spectrum disorder. Autism Research Official Journal of the International Society for Autism Research, 10( 10), 1629-1652. |
| [46] | Maskey M., Lowry J., Rodgers J., Mcconachie H., & Parr J. R . ( 2014). Reducing specific phobia/fear in young people with autism spectrum disorders (asds) through a virtual reality environment intervention. Plos One, 9( 7), e100374. |
| [47] | Matson J. L., Lovullo S. V., Rivet T. T., & Boisjoli J. A . ( 2009). Validity of the autism spectrum disorder-comorbid for children (asd-cc). Research in Autism Spectrum Disorders, 3( 2), 345-357. |
| [48] | Mazefsky C. A., & Herrington, J .( 2014). Autism and anxiety: Etiologic factors and transdiagnostic processes. Handbook of autism and anxiety. Springer International Publishing. |
| [49] | Neil, L. ( 2016). The relationship between intolerance of uncertainty, sensory sensitivities, and anxiety in autistic and typically developing children. Journal of Autism and Developmental Disorders, 46( 6), 1962-1973. |
| [50] | Ozsivadjian A., Hibberd C., & Hollocks M. J . ( 2013). Brief report: The use of self-report measures in young people with autism spectrum disorder to access symptoms of anxiety, depression and negative thoughts. Journal of Autism & Developmental Disorders, 44( 4), 969-974. |
| [51] | Pelphrey K. A., & Carter, E. J. ( 2010). Brain mechanisms for social perception: Lessons from autism and typical development. Annals of the New York Academy of Sciences, 1145, 283-299. |
| [52] | Pessoa L., & Adolphs R. ( 2010). Emotion processing and the amygdala: From a ‘low road’ to ‘many roads’ of evaluating biological significance. Nature Reviews Neuroscience, 11( 11), 773-783. |
| [53] | Rieske R. D., Matson J. L., Davis III T. E., Konst M. J., Williams L. W., & Whiting S. E . ( 2013). Examination and validation of a measure of anxiety specific to children with autism spectrum disorders. Pediatric Rehabilitation, 16( 1), 9-16. |
| [54] | Robertson A. E., Stanfield A. C., Watt J., Barry F., Day M., Cormack M., & Melville C . ( 2018). The experience and impact of anxiety in autistic adults: A thematic analysis. Research in Autism Spectrum Disorders, 46, 8-18. |
| [55] | Rodgers J., & Ofield A. ( 2018). Understanding, recognising and treating co-occurring anxiety in autism. Current Developmental Disorders Reports, 5( 1), 58-64. |
| [56] | Rodgers J., Glod M., Connolly B., & McConachie H . ( 2012). The relationship between anxiety and repetitive behaviours in autism spectrum disorder. Journal of Autism and Developmental Disorders, 42( 11), 2404-2409. |
| [57] | Rodgers J., Wigham S., Mcconachie H., Freeston M., Honey E., & Parr J. R . ( 2016). Development of the anxiety scale for children with autism spectrum disorder (asc-asd). Autism Research Official Journal of the International Society for Autism Research, 9( 11), 1205-1215. |
| [58] | Rosen T. E., Connell J. E., & Kerns C. M . ( 2016). A review of behavioral interventions for anxiety-related behaviors in lower-functioning individuals with autism. Behavioral Interventions, 31( 2), 120-143. |
| [59] | Rotheram-Borus M. J., Swendeman D., & Chorpita B. F . ( 2012). Disruptive innovations for designing and diffusing evidence-based interventions. American Psychologist, 67( 6), 463-476. |
| [60] | Schoneveld E. A., Malmberg M., Lichtwarck-Aschoff A., Verheijen G. P., Engels R. C. M. E., & Granic I . ( 2016). A neurofeedback video game (mindlight) to prevent anxiety in children: A randomized controlled trial. Computers in Human Behavior, 63, 321-333. |
| [61] | Singh, S. ( 2012). Language and cognitive behavioural therapy practice paper-literature review and case example. Journal of Cognitive-Behavioral Psychotherapy and Research, 1( 3), 138-144. |
| [62] | Sung M., Ooi Y. P., Goh T. J., Pathy P., Fung D. S. S., Ang R. P., .. Lam C. M . ( 2011). Effects of cognitive-behavioral therapy on anxiety in children with autism spectrum disorders: A randomized controlled trial. Child Psychiatry & Human Development, 42( 6), 634-649. |
| [63] | Swain D., Scarpa A., White S., & Laugeson E . ( 2015). Emotion dysregulation and anxiety in adults with asd: Does social motivation play a role? Journal of Autism & Developmental Disorders, 45( 12), 3971-3977. |
| [64] | Thorson R. T., & Matson, J. L. ( 2012). Cutoff scores for the autism spectrum disorder - comorbid for children (asd-cc). Research in Autism Spectrum Disorders, 6( 1), 556-559. |
| [65] | Top D. N., Stephenson K. G., Doxey C. R., Crowley M. J., Kirwan C. B., & South M . ( 2016). Atypical amygdala response to fear conditioning in autism spectrum disorder. Biological Psychiatry Cognitive Neuroscience & Neuroimaging, 1( 4), 308-315. |
| [66] | Uljarevic M., Nuske H., & Vivanti, G .( 2016). Anxiety in autism spectrum disorder. Psychiatric symptoms and comorbidities in autism spectrum disorder. Springer International Publishing.. |
| [67] | van Steensel, F. J. A., Bögels S. M., & Perrin S . ( 2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical Child and Family Psychology Review, 14, 302-317. |
| [68] | van Steensel, F. J. A., Deutschman A. A., & Bögels S. M . ( 2013). Examining the screen for child anxiety-related emotional disorder-71 as an assessment tool for anxiety in children with high-functioning autism spectrum disorders. Autism the International Journal of Research & Practice, 17( 6), 681-692. |
| [69] | van Steensel, F. J. A., & Heeman, E. J. ( 2017). Anxiety levels in children with autism spectrum disorder: A meta-analysis. Journal of Child & Family Studies, 26( 7), 1753-1767. |
| [70] | Vasa R. A., Mazurek M. O., Mahajan R., Bennett A. E., Bernal M. P., Nozzolillo A. A., .. Coury D. L . ( 2016). Assessment and treatment of anxiety in youth with autism spectrum disorders. Pediatrics, 137( Sup.), S115-S123. |
| [71] | Walters S., Loades M., & Russell A . ( 2016). A systematic review of effective modifications to cognitive behavioural therapy for young people with autism spectrum disorders. Review Journal of Autism & Developmental Disorders, 3( 2). 137-153. |
| [72] | White S. W., Lerner M. D., Mcleod B. D., Wood J. J., Ginsburg G. S., Kerns C., .. Compton S . ( 2015). Anxiety in youth with and without autism spectrum disorder: Examination of factorial equivalence. Behavior Therapy, 46( 1), 40-53. |
| [73] | White S. W., Mazefsky C. A., Dichter G. S., Chiu P. H., Richey J. A., & Ollendick T. H . ( 2014). Social-cognitive, physiological, and neural mechanisms underlying emotion regulation impairments: Understanding anxiety in autism spectrum disorder. International Journal of Developmental Neuroscience, 39, 22-36 |
| [74] | White S. W., Oswald D., Ollendick T., & Scahill L . ( 2009). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29( 3), 216-229. |
| [75] | White S. W., Schry A. R., & Maddox B. B . ( 2012). Brief report: The assessment of anxiety in high-functioning adolescents with autism spectrum disorder. Journal of Autism & Developmental Disorders, 42( 6), 1138-1145. |
| [76] | Wigham S., Rodgers J., South M., Mcconachie H., & Freeston M . ( 2015). The interplay between sensory processing abnormalities, intolerance of uncertainty, anxiety and restricted and repetitive behaviours in autism spectrum disorder. Journal of Autism & Developmental Disorders, 45( 4), 943-952. |
| [77] | Wijnhoven L. A. M. W., Creemers D. H. M., Engels R. C. M. E., & Granic I . ( 2015). The effect of the video game mindlight on anxiety symptoms in children with an autism spectrum disorder. BMC Psychiatry, 15, 1(2015-07-01). |
| [78] | Wood J. J., & Gadow, K. D. ( 2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology Science & Practice, 17( 4), 281-292. |
| [79] | Zainal H., Magiati I., Tan J. W-L., Sung M., Fung D. S. S., & Howlin P . ( 2014). A preliminary investigation of the spence children's anxiety parent scale as a screening tool for anxiety in young people with autism spectrum disorders. Journal of Autism & Developmental Disorders, 44( 8), 1982-1995. |
| [80] | Zandt F., Prior M., & Kyrios M . ( 2007). Repetitive behavior in children with high functioning autism and obsessive compulsive disorder. Journal of Autism and Developmental Disorders, 37( 2), 251-259. |
相关文章 15
| [1] | 叶友才, 林荣茂, 严由伟. 树大招风：社交焦虑者的正性评价恐惧[J]. 心理科学进展, 2021, 29(6): 1056-1066. |
| [2] | 霍超, 李祚山, 孟景. 自闭症谱系障碍个体的共情干预：扬长还是补短?[J]. 心理科学进展, 2021, 29(5): 849-863. |
| [3] | 赵小红, 童薇, 陈桃林, 吴冬梅, 张蕾, 陈正举, 方晓义, 龚启勇, 唐小蓉. 敬畏的心理模型及其认知神经机制[J]. 心理科学进展, 2021, 29(3): 520-530. |
| [4] | 贾磊, 徐玉帆, 王成, 任俊, 汪俊. γ节律神经振荡：反映自闭症多感觉整合失调的一项重要生物指标[J]. 心理科学进展, 2021, 29(1): 31-44. |
| [5] | 何姣, 白宝玉, 夏勉. 心理治疗中的脱落[J]. 心理科学进展, 2020, 28(7): 1187-1198. |
| [6] | 陈子晨, 姜鹤. 心理健康服务的文化胜任力：理论取向与实践策略[J]. 心理科学进展, 2020, 28(4): 661-672. |
| [7] | 尹倩兰, 陈艾彬, 邓光辉. 体像障碍的认知机制及治疗[J]. 心理科学进展, 2020, 28(2): 275-283. |
| [8] | 冉光明, 李睿, 张琪. 高社交焦虑者识别动态情绪面孔的神经机制[J]. 心理科学进展, 2020, 28(12): 1979-1988. |
| [9] | 刘慧晨, 陈坚. 婴儿的痛觉[J]. 心理科学进展, 2020, 28(10): 1723-1732. |
| [10] | 明志君, 陈祉妍. 心理健康素养：概念、评估、干预与作用[J]. 心理科学进展, 2020, 28(1): 1-12. |
| [11] | 区健新, 吴寅, 刘金婷, 李红. 计算精神病学：抑郁症研究和临床应用的新视角[J]. 心理科学进展, 2020, 28(1): 111-127. |
| [12] | 李泰安, 张禹, 李杰. 多目标追踪在各类人群评价与训练中的应用[J]. 心理科学进展, 2019, 27(9): 1585-1595. |
| [13] | 张亚利, 李森, 俞国良. 自尊与社交焦虑的关系：基于中国学生群体的元分析[J]. 心理科学进展, 2019, 27(6): 1005-1018. |
| [14] | 高见, 王鹏翀, 李占江. 认知行为治疗的生物学机制[J]. 心理科学进展, 2019, 27(3): 522-532. |
| [15] | 秦海霞, 赵文瑞, 喻婧, 雷旭. 失眠患者静息态脑网络的改变：网络内与网络间的功能连接异常[J]. 心理科学进展, 2019, 27(2): 289-300. |
PDF全文下载地址:
http://journal.psych.ac.cn/xlkxjz/CN/article/downloadArticleFile.do?attachType=PDF&id=4803
