基于纳米氢氧化铝颗粒的Pickering乳液制备

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吴楠^1,2，吴颉^2*，苗春宇²，马光辉^1,2，安文琪³

1. 中国科学院大学化学工程学院，北京 1000492. 中国科学院过程工程研究所生化工程国家重点实验室，北京 1001903. 华兰生物工程股份有限公司，河南新乡 453003

收稿日期:2019-02-28修回日期:2019-03-26出版日期:2019-12-22发布日期:2019-12-22
通讯作者:吴颉

基金资助:中国科学院国际合作局国际伙伴计划项目

Preparation of Pickering emulsion based on alumina hydroxide nanoparticles

Nan WU^1,2, Jie WU^2*, Chunyu MIAO², Guanghui MA^1,2, Wenqi AN ³

1. School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, China2. National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China3. Hualan Biological Engineering Co., Ltd., Xinxiang, Henan 453003, China

Received:2019-02-28Revised:2019-03-26Online:2019-12-22Published:2019-12-22
Contact:WU Jie

摘要/Abstract

摘要： 以异丙醇铝为原料，采用醇盐水解?水热法制备勃姆石型纳米氢氧化铝颗粒，优化制备条件；以所制颗粒为稳定剂、角鲨烯为油相，通过超声破碎法制备Pickering乳液，考察了颗粒浓度、水相成分、超声时间及功率对Pickering乳液粒径及稳定性的影响。结果表明，水热温度200℃、水热时间2 h条件下，可制得结晶度高且均一的勃姆石型纳米氢氧化铝颗粒，平均粒径为55.70?9.20 nm，多分散性指数(PDI)为0.187?0.011；所制Pickering乳液平均粒径为1870?55 nm，PDI=0.120?0.010，可在室温下稳定储存120 d以上，且生物相容性良好，有望应用于生物医药领域。

引用本文

吴楠吴颉苗春宇马光辉安文琪. 基于纳米氢氧化铝颗粒的Pickering乳液制备[J]. 过程工程学报, 2019, 19(6): 1220-1227.
Nan WU Jie WU Chunyu MIAO Guanghui MA Wenqi AN. Preparation of Pickering emulsion based on alumina hydroxide nanoparticles[J]. Chin. J. Process Eng., 2019, 19(6): 1220-1227.

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