摘要/Abstract

以醇为酰基化试剂，在水溶液条件下，发展了一种简便、高效的钯催化氧化偶氮苯酰基化反应体系.在此体系中，醇被氧化为醛，实现氧化偶氮苯的邻位酰基化反应，具有很好的区域选择性，以中等到较高收率得到酰基化的氧化偶氮苯衍生物，底物的普适性较好.
关键词: 钯催化, 氧化偶氮苯, 酰基化, 绿色化学
A facile and efficient protocol for palladium-catalyzed ortho-acylation of azoxybenzenes has been developed under aqueous conditions. In this process, the alcohols were oxidized into the corresponding aldehydes in situ, which coupled with azoxybenzenes with excellent regioselectivity, affording the acylated azoxybenzenes in moderate to good yields. A variety of functional groups were tolerated in this procedure.


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