摘要/Abstract

具有五元环和三配体结构的五配位氧磷烷（ab₂）在碱催化条件下自发进行分子间的配体交换反应，产生不同配体组合的全部三种五配位氧磷烷（a₃，b₃和a₂b）.如果把其中a₃与b₃作为父代分子，其配体交换产生的五配位氧磷烷a₂b和ab₂可以视作子代分子，从而自发实现了分子结构的多样化.因此，五配位氧磷烷分子间配体交换反应可以作为研究生命过程中具有五配位磷中间体结构化学性质的模型，对理解基因转录和生命信息储存等过程中涉及的RNA分子剪接、水解和融合等重要生命过程的分子机制提供了重要依据.
关键词: 磷化学, 五配位氧磷烷, 配体交换, 有机化学模型
Penta-coordinated phosphoranes (ab₂) with a five-member cycle and three ligands would simultaneously exchange with themselves under base catalysis to form three different penta-oxy phosphoranes with all the combinatorial ligands referred as a₃, b₃, and a₂b. If we consider a₃ and b₃ as parents, the products obtained from exchange, namely a₂b and ab₂, could be regarded as the offspring of the first generation, leading to the diversified chemical structures. Thus, these fascinating reactions could be considered as a promising chemical model for studying the unique chemistry of possible penta-coordinated phosphorus intermediates in the process of RNA self-splicing, hydrolysis and fusion for gene transcription and biological information storage.
Key words: phosphorus chemistry, penta-oxy phosphorane, ligand exchange, organic chemical model


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