摘要/Abstract

利用相对廉价易得、操控简便的三氟甲基磺酰氯为三氟甲基自由基前体，在可见光催化下通过非活化烯烃的自由基1，2-烷氧基-三氟甲基化反应实现了一系列三氟甲基化的四氢呋喃和四氢吡喃化合物的高效合成.
关键词: 三氟甲基磺酰氯, 四氢呋喃, 四氢吡喃, 可见光, 烷氧-三氟甲基化
An efficient protocol for facile access to trifluoromethylated tetrahydrofuran and tetrahydropyran has been developed under visible light irradiation conditions via radical 1,2-alkoxyl-trifluoromethylation of unactivated alkene. It features the use of readily commercially available and operatively simple trifluoromethanesulfonyl chloride as a trifluoro- methyl radical source, thus making the protocol potentially appealing for practical preparation.
Key words: trifluoromethanesulfonyl chloride, tetrahydrofuran, tetrahydropyran, visible light, alkoxyl-trifluoromethylation


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