Professor LI Gang 李刚
MBBS(4 MMU, China), D. Phil(Oxon)
Professor of Orthopaedics and Traumatology
矫形外科及创伤学系教授

BIOGRAPHY
Gang Li is a non-clinical full professor (since 2009) in the Department of Orthopedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong. Previous to this appointment, he was Lecturer, Senior Lecturer and Reader (1998-2009), at Department of Orthopaedic Surgery, School of Medicine, Queen's University, Belfast, UK.
Prof. Li earned an MBBS at the Fourth Military Medical University, Xian, China (1991), and a D. Phil at the University of Oxford School of Medicine, England, UK (1998). The focus of his research are on studies of the biological mechanisms of distraction osteogenesis, stem cell biology, circulating mesenchymal stem cells (MSCs), the use of MSCs for cell therapy applications, musculoskeletal tissue regeneration and repair.
Prof. Li has published more than 220 peer-reviewed SCI articles with citations over 4500 and H index 40; 15 book chapters, edited 3 books on tissue engineering, distraction histogenesis, leg-lengthening and Ilizarov techniques. He is a council member of Chinese Orthopaedic Research Society; Tissue Engineering and Regenerative Medicine Society, Chinese Association of Biomedical Engineering; Vice Chairman, Division of Regenerative Biomaterials, Chinese Association of Biomaterials; Chairman of ILLRS and ASAMI China Branch. He is associate editor for Journal of Orthopaedic Translation; editor for Calcified Tissue International, Bone and Joint Research, and Bone. He holds honorary or visiting Professorship at many prestigious universities such as Monash University, Australia; University of Malaya, Malaysia; Sichuan University, China; South-East University Medical School, China; The Airforce Medical University, China; Guangdong Medical University and Jilin University, China. His work received serval awards including the 1st Class Research Award in Science and Technology, Ministry of Education, China; 2nd Class Award in Medical Science and Technology, China Medical Association; 1st Class Award in China Medical Science, China International Exchange and Promotion Association for Medical and Healthcare.

EXPERTISE Stem Cell Therapy Clinical Applications
Limb Deformity Correction and Reconstruction

SPECIALISED RESEARCH AREAS Distraction Osteogenesis Mechanisms and Novel Clinical Applications
Stem Cell Biology and Cellular Therapies
Musculoskeletal Tissue Engineering

SELECTED PUBLICATION
1. Xu J, Feng Q, Lin S, Yuan W, Li R, Li J, Wei K, Chen X, Zhang K, Yang Y, Wu T, Wang B, Zhu M, Guo R, Li G*, Bian L. Injectable stem cell-laden supramolecular hydrogels enhance in situ osteochondral regeneration via the sustained co-delivery of hydrophilic and hydrophobic chondrogenic molecules. Biomaterials. 2019 Jul; 210:51-61.

2. Kang H, Yang BG, Zhang KY, Pan Q, Yuan WH, Li G*, Bian LM. Immunoregulation of macrophages by dynamic ligand presentation via ligand–cation coordination. Nature Communication, 2019 April; 10(1):1696.

3. Kang H, Wong SHD, Pan Q, Li G*, Bian L. Anisotropic ligand nanogeometry modulates the adhesion and polarization state of macrophages. Nano Lett. 2019 Mar; 19(3):1963-1975.

4. Lin WP, Xu LL, Pa Q, Lin SE, Feng L, Wang B, Chen SX, Li Y, Wang HX, Li YC, Wang Y, Lee WYW, Sun D, Li G*. Lgr5-overexpressing mesenchymal stem cells augment fracture healing through regulation of Wnt/ERK signaling pathways and mitochondrial dynamics. The FASEB Journal, 2019, 2019 Apr 16.

5. Lin SE, Cui L, Chen GH, Huang JP, Yang YH, Zou KJ, Lai YX, Wang XL, Zuo LY, Wu T, Cheng JCY, Li G*, Wei B, Lee WYW. PLGA/β-TCP composite scaffold incorporating salvianolicacid B promotes bone fusion by angiogenesis and osteogenesis in a rat spinal fusion model. Biomaterials, 2019 March, 196: 109-121.

6. Xu J, Sun YX, Wu TY, Liu Y, Shi L, Zhang JF, Kang QL, Chai YM, Li G*. Enhancement of bone regeneration with the accordion technique via HIF-1α/VEGF activation in a rat distraction osteogenesis model. Journal of Tissue Engineering and Regenerative Medicine, 2018 Feb;12(2):e1268-e1276.

7. Xu LL, Liu YM, Sun YX, Wang B, Xiong YP, Lin WP, Wei QS, Wang HB, He W, Wang B, Li G*. Tissue source determines the differentiation potentials of mesenchymal stem cells- a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue. Stem Cell Research & Therapy, 2017 Dec; 8(1):275.

8. Lin SE, Lee WYW, Feng Q, Xu LL, Wang B, Man GCW, Chen YF, Jiang XH, Bian LM, Cui L, Wei B, Li G*. Synergistic effects on mesenchymal stem cell-based cartilage regeneration by chondrogenic preconditioning and mechanical stimulation. Stem Cell Research & Therapy, 2017 Oct; 8(1):221.

9. Wang B, Lee WYW, Huang B, Zhang JF, Wu TY, Jiang XH, Wang CC, Li G*. Secretome of human fetal mesenchymal stem cells ameliorates replicative senescence of human adult mesenchymal stem cells. Stem Cells and Development, 2016 Oct; 347(2):360-6.

10. Yin Zi, Guo J, Wu TY, Chen X, Xu LL, Lin SE, Sun YX, Chan KM, Ouyang HW, Li G*. Stepwise differentiation of mesenchymal stem cells augments tendon-like tissue formation and defect repair in vivo. Stem Cells Translational Medicine, 2016 Aug; 5(8):1106-16.

























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