Professor CHEUNG Wing-hoi, Louis 张颖恺
BSc(Hons), PhD, PgCert(Biostatistics)
Professor of Orthopaedics and Traumatology
矫形外科及创伤学系教授
Deputy Director of Musculoskeletal Research Laboratory
骨关节肌肉研究实验室副主任
Deputy Director of MSc in Musculoskeletal Medicine, Rehabilitation and Geriatric Orthopaedics Programmes
骨关节医学、康复及老年骨科理学硕士课程副主任

BIOGRAPHY
Professor Cheung is graduated as PhD in Department of Orthopaedics & Traumatology, CUHK in 2000 and joined as academic staff in 2005. He is also a Programme Committee Member of Biomedical Engineering Programme, Faculty of Engineering, CUHK and Member of Management Committee on the Laboratory Animal Services Centre. He serves as reviewers for AO Foundation and Annual Meeting of Orthopaedic Research Society (ORS); meanwhile, he is editorial board members of 7 international journals and ad hoc reviewers of over 50 professional journals. He is an active member of ORS, ISFR and ICMRS. He has published over 100 peer-reviewed international articles, 8 book chapters, over 300 conference abstracts and contributes as 1 book editor. He was awarded with Berton Rahn Research Fund of AO Foundation in 2013 and Healthstar Osteoporosis Medical-Research Award (HOMA) in 2020. He also obtains 3 patents (1 PCT and 2 US/China).

EXPERTISE Animal Model
Bone Densitometry
Histomorphometry

SPECIALISED RESEARCH AREAS Osteoporotic Fracture Healing and Sarcopenia
Mechanical Stimulation
Biophysical Intervention


SELECTED PUBLICATION
1. Cheung WH*, Hung VWY, Cheuk KY, Chau WW, Tsoi KKF, Wong RMY, Chow SKH, Lam TP, Yung PSH, Law SW, Qin L. Best performance parameters of HR-pQCT to predict fragility fracture – systematic review and meta-analysis. J Bone Miner Res. 2021. [Online ahead of print]

2. Cheng KYK, Chow SKH, Hung VWY, Wong CHW, Wong RMY, Tsang CSL, Kwok T, Cheung WH*. Diagnosis of sarcopenia by evaluating skeletal muscle mass by adjusted bioimpedance analysis (BIA) validated with DXA. J Cachexia Sarcopenia Muscle. 2021. [Online ahead of print]

3. Liu C, Cheung WH*, Li J, Chow SKH, Yu J, Wong SH, Ip M, Sung JJY, Wong RMY. Understanding the gut microbiota and sarcopenia: a systematic review. J Cachexia Sarcopenia Muscle. 2021. [Online ahead of print]

4. Wong RMY, Choy MHV, Li J, Li TK, Chim YN, Li MCM, Cheng JCY, Leung KS, Chow SKH, Cheung WH*. Fibrinolysis as a target to enhance osteoporotic fracture healing by vibration therapy in a metaphyseal fracture model. Bone Joint Res. 10(1):41-50, 2021.

5. Chui CS, Leung KS, Qin JH, Shi DF, Augat P, Wong RMY, Chow SKH, Huang XY, Chen CY, Lai YX, Yung PSH, Qin L, Cheung WH*. Population-based and personalized design of total knee replacement prosthesis for additive manufacturing based on Chinese anthropometric data. Engineering. 7(3):386-94, 2021.

6. Bao Z, Cui C, Chow SKH, Qin L, Wong RMY, Cheung WH*. AChRs degeneration at NMJ in ageing-associated sarceopnia – a systematic review. Front Aging Neurosci. 12:597811, 2020.

7. Wang J, Cui C, Chim YN, Yao H, Shi L, Xu J, Wang J, Wong RMY, Leung KS, Chow SKH, Cheung WH*. Vibration and HMB suppresses intramuscular fat infiltration and adipogenic differentiation in sarcopenic mice. J Cachexia Sarcopenia Muscle. 11:564-77, 2020.

8. Choy MHV, Wong RMY, Li MC, Wang BY, Liu XD, Lee W, Cheng JCY, Chow SKH, Cheung WH*. Can we enhance osteoporotic metaphyseal fracture healing through enhancing ultrastructual and functional changes of osteocytes in cortical bone with low-magnitude high-frequency vibration? FASEB J. 34(3):4234-4252, 2020.

9. Qin JH, Chow SK, Guo AY, Wong WN, Leung KS, Cheung WH*. Low magnitude high frequency vibration accelerated cartilage degeneration but improved epiphyseal bone formation in anterior cruciate ligament transection induced osteoarthritis rat model. Osteoarthritis Cartilage. 27(7):1061-7, 2014.

10. Leung KS, Li CY, Tse YK, Choy TK, Leung PC, Hung VWY, Chan SY, Leung AH, Cheung WH*. Effects of 18-month low-magnitude high-frequency vibration on fall rate and fracture risks in 710 community elderly – a cluster randomized controlled trial. Osteoporos Int. 25:1785-95, 2014.


SELECTED AWARDS
1. 学科成就奖: 第十届中国药学发展奖康辰骨质疏松医药研究奖 (HOMA), 2020

2. 壹等奖： 通用型骨科导航手术机器人系统关键技术研发与临床应用。北京市科学技术奖, 2018

3. Shihao Liu-Xianyi Zhu Memorial Best Paper Award: Activated osteocytes and enhanced mineralization in osteoporotic metaphyseal fracture healing model augmented with cyclic mechanical loading. 9th International Conference on Osteoporosis and Bone Research. Suzhou, China. 2018

4. Best Paper Award for Associate Member: Influence of sarcopenia on osteoporotic fracture healing in senescence accelerated mouse model. The 36th Annual Congress of Hong Kong Orthopaedic Association. Hong Kong. 2016

5. Berton Rahn Research Fund Prize Award: AO Foundation, Switzerland. Lima, Peru. 2013

























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