{ "chinesename
黄炜燊
title
Prof.
surname
Wong
givenname
Vincent WS
photo
../images/people/vincentwong.png
education
MBChB (Hons), MD (CUHK), FRCP (Edin), FHKCP, FHKAM (Medicine)
post
Mok Hing Yiu Professor of Medicine, Department of Medicine & Therapeutics
Head, Division of Gastroenterology and Hepatology
Director, Cheng Suen Man Shook Centre for Hepatitis Research
Deputy Director, Center for Liver Health
Faculty of Medicine, The Chinese University of Hong Kong
Honorary Consultant, Prince of Wales Hospital, Hospital Authority
researcherid
K-3864-2014
expertise
Non-alcoholic fatty liver disease, viral hepatitis
interest
Non-invasive assessment and treatment of chronic liver diseases
tel
(852) 3505 1420
email
wongv@cuhk.edu.hk
research
We established the fatty liver research team in 2004 to study the natural history, novel investigations and treatment of non-alcoholic fatty liver disease (NAFLD). In collaboration with other European and Asian centers, we performed a series of studies to define the clinical use of transient elastography in NAFLD patients (Hepatology 2010, J Hepatol 2012, Am J Gastroenterol 2012, J Hepatol 2017). In addition, we pioneered the use of proton-magnetic resonance spectroscopy to quantify liver fat. Using these state-of-the-art tests, we found that 27% of the general adult population in Hong Kong suffers from NAFLD, of which 4% also have severe fibrosis or cirrhosis (Gut 2012). We further showed that over 10% of diabetic patients might have severe liver fibrosis or cirrhosis (Gut 2016).

Our current programme is focused on biomarkers for NAFLD severity and early liver cancer detection (J Hepatol 2012, Hepatology 2013). We are also one of the leading sites in international drug trials for non-alcoholic steatohepatitis.

selected
publication
Wong VW, Petta S, Hiriart JB, Cammà C, Wong GL, Marra F, Vergniol J, Chan AW, Tuttolomondo A, Merrouche W, Chan HL, Le Bail B, Arena U, Craxì A, de Lédinghen V. Validity criteria for the diagnosis of fatty liver by M probe-based controlled attenuation parameter. J Hepatol 2017;67:577-584."},{ "publication
Leung JC, Loong TC, Wei JL, Wong GL, Chan AW, Choi PC, Shu SS, Chim AM, Chan HL, Wong VW. Histological severity and clinical outcomes of nonalcoholic fatty liver disease in nonobese patients. Hepatology 2017;65:54-64."},{ "publication
Kwok R, Choi KC, Wong GL, Zhang Y, Chan HL, Luk AO, Shu SS, Chan AW, Yeung MW, Chan JC, Kong AP, Wong VW. Screening diabetic patients for non-alcoholic fatty liver disease with controlled attenuation parameter and liver stiffness measurements: a prospective cohort study. Gut 2016;65:1359-68."},{ "publication
Wong VW, Wong GL, Yeung JC, Fung CY, Chan JK, Chang ZH, Kwan CT, Lam HW, Limquiaco J, Chim AM, Yu CM, Chan HL. Long-term clinical outcomes after fatty liver screening in patients undergoing coronary angiogram: A prospective cohort study. Hepatology 2016;63:754-63."},{ "publication
Wong VW, Wong GL, Yeung DK, Lau TK, Chan CK, Chim AM, Abrigo JM, Chan RS, Woo J, Tse YK, Chu WC, Chan HL. Incidence of non-alcoholic fatty liver disease in Hong Kong: a population study with paired proton-magnetic resonance spectroscopy. J Hepatol 2015;62:182-9."},{ "publication
Wong VW, Chan RS, Wong GL, Cheung BH, Chu WC, Yeung DK, Chim AM, Lai JW, Li LS, Sea MM, Chan FK, Sung JJ, Woo J, Chan HL. Community-based lifestyle modification programme for non-alcoholic fatty liver disease: A randomized controlled trial. J Hepatol 2013;59:536-42."},{ "publication
Wong VW, Chu WC, Wong GL, Chan RS, Chim AM, Ong A, Yeung DK, Yiu KK, Chu SH, Woo J, Chan FK, Chan HL. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: A population study using proton-magnetic resonance spectroscopy and transient elastography. Gut 2012;61:409-15."},{ "publication
Wong VW, Wong GL, Tsang SW, Fan T, Chu WC, Woo J, Chan AW, Choi PC, Chim AM, Lau JY, Chan FK, Sung JJ, Chan HL. High prevalence of colorectal neoplasm in patients with non-alcoholic steatohepatitis. Gut 2011;60:829-36."},{ "publication
Wong VW, Chan SL, Mo F, Chan TC, Loong HH, Wong GL, Lui YY, Chan AT, Sung JJ, Yeo W, Chan HL, Mok TS. Clinical scoring system to predict hepatocellular carcinoma in chronic hepatitis B carriers. J Clin Oncol 2010;28:1660-5."},{ "publication
Wong VW, Vergniol J, Wong GL, Foucher J, Chan HL, Le Bail B, Choi PC, Kowo M, Chan AW, Merrouche W, Sung JJ, de Lédinghen V. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology 2010;51:454-62." }]}