{ "chinesename
高浩
title
Prof.
surname
KO
givenname
Owen H
photo
../images/people/owenko.png
education
BMedSc, MBChB (CUHK), PhD (UCL)
post
Assistant Professor (non-clinical), Department of Medicine & Therapeutics Faculty of Medicine, The Chinese University of Hong Kong
researcherid
expertise
Optical instrumentation, Electrophysiology, Image processing
interest
Visual neuroscience, Neurovascular biology and cerebral small vessels disease
tel
(852) 2558 7122
email
ho.ko@cuhk.edu.hk
research
Research in my laboratory currently focuses on three schemes: Circuitry mechanisms underlying sensory perception, with a particular focus on visionDevelopment of basic, bottom up approach to study how cardiovascular risk factors and genetic factors determine the development of cerebral small vessels diseaseDevelopment of novel MRI contrast agents for in vivo imaging and diagnosis of neurodegenerative diseases

selected
publication
Okun M, Steinmetz N, Cossell L, Iacaruso MF, Ko H, Barthó P, Moore T, Hofer SB, Mrsic-Flogel TD, Carandini M, Harris KD. Diverse coupling of neurons to populations in sensory cortex. Nature. 2015 Apr 6. doi: 10.1038/nature14273." },{ "publication
Cossell L, Iacaruso MF, Muir DR, Houlton R, Sader EN, Ko H, Hofer SB, Mrsic-Flogel TD. Functional organization of excitatory synaptic strength in primary visual cortex. Nature. 2015 Feb 19; 518(7539):399-403." },{ "publication
Ko H. Functional organization of synaptic connectivity in the neocortex. Runner-up essay, Eppendorf and Science Prize for Neurobiology 2014. Science. 2014 Oct 31; 346(6209):555." },{ "publication
Huang Y, Yoon K, Ko H, Jiao S, Ito W, Wu JY, Yung WH, Lu B, Morozov A. 5-HT3a receptors modulate hippocampal gamma oscillations by regulating synchrony of parvalbumin-positive interneurons. Cerebral Cortex. 2014 Sep 21. pii: bhu209." },{ "publication
Ko H, Mrsic-Flogel TD, Hofer SB. Emergence of feature-specific connectivity in cortical microcircuits in the absence of visual experience. The Journal of Neuroscience. 2014 Jul 16; 34(29):9812-6." },{ "publication
Ko H, Cossell L, Baragli C, Antolik J, Clopath C, Hofer SB, Mrsic-Flogel TD. The emergence of functional microcircuits in visual cortex. Nature. 2013 Apr 4; 496(7443):96-100." },{ "publication
Li Q, Ke Y, Chan DCW, Qian ZM, Yung KKL, Ko H, Arbuthnott GW, Yung WH. Therapeutic deep brain stimulation in parkinsonian rats directly influences motor cortex. Neuron. 2012 Dec 6; 76(5):1030-41." },{ "publication
Huang Y, Ko H, Cheung ZH, Yung KK, Yao T, Wang JJ, Morozov A, Ke Y, Ip NY, Yung WH. Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons. Experimental Neurology. 2012 Feb; 233(2):791-8." },{ "publication
Hofer SB, Ko H (co-1st author), Pichler B, Vogelstein J, Ros H, Zeng H, Lein E, Lesica NA, Mrsic-Flogel TD. Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex. Nature Neuroscience. 2011 Jul 17; 14(8):1045-52." },{ "publication
Ko H, Hofer SB, Pichler B, Buchanan KA, Sj?str?m PJ, Mrsic-Flogel TD. Functional specificity of local synaptic connections in neocortical networks. Nature. 2011 May 5; 473(7345):87-91." }]}