) 山东师范大学心理学院, 济南 250358
收稿日期:2020-07-09出版日期:2021-03-15发布日期:2021-01-26通讯作者:贾世伟E-mail:jiashiwei82@126.com基金资助:国家自然科学基金青年项目(NSFC31200784)Feedback-related negativity: A biomarker for depression
QIN Haofang, HUANG Rong, JIA Shiwei() School of Psychology, Shandong Normal University, Jinan 250358, China
Received:2020-07-09Online:2021-03-15Published:2021-01-26Contact:JIA Shiwei E-mail:jiashiwei82@126.com摘要/Abstract
摘要： 反馈相关负波(feedback-related negativity, FRN)是一种反映个体奖赏敏感性的脑电成分; 而抑郁症患者的特征之一是奖赏敏感性的减弱。大量横向研究发现了重度抑郁症患者(major depressive disorder, MDD)及有患抑郁症风险群体的FRN异常; 另外, 纵向研究发现FRN的异常能够预测青春期抑郁发作及抑郁症状发展, 压力、睡眠等因素在其中起调节作用。这提示FRN可能在对抑郁症的诊断及分型、抑郁高危群体的筛查及干预等方面具有潜在价值。目前关于FRN的心理功能依然存在一些争议, 在未来的研究中应该进一步明确FRN的功能和测量方法, 并探明抑郁症的异质性和共病对FRN的作用, 也应关注老年人群体中FRN与抑郁症的关系。
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