导师姓名： 李红 专业代码： 100214
性别： 女 专业名称： 肿瘤学
培养单位： 附属仁济医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： hongli@shsci.org
邮编： 200032 邮箱地址： hongli@shsci.org

研究方向 (点击浏览详细信息)
消化系统肿瘤转移的研究； 肿瘤分子靶向治疗新靶点鉴定

社会任职
中国医师协会临床精准医疗专业委员会癌症代谢与治疗专业委员会委员
上海市医学会肿瘤靶分子专科分会委员
上海市医学会肿瘤分会第十届青年委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2018BR20 精子相关抗原4促进肝细胞癌转移的作用及分子机制研究 2018年上海市卫生计生系统优秀学科带头人 2018-07~2021-06 45万元 课题负责人
** PEDF促进肝细胞癌转移的功能及分子机制研究 国家自然科学基金 2017-01~2020-12 53万元 课题负责人
** 利用条件性基因敲除小鼠研究ANGPTL4 在肝癌发生中的作用及机制 国家自然科学基金 2014-01~2017-12 75万元 课题负责人
** ANGPTL4在肺癌转移中的作用及分子机制研究 国家自然科学基金 2013-01~2015-12 23万元 课题负责人
13ZZ082 利用条件性基因敲除小鼠研究ANGPTL4基因在肝癌发生发展中功能及机制 上海市教委创新项目 2013-01~2015-12 16万元 课题负责人
08ZR** ANGPTL4影响肝癌转移的分子机制 上海市科委，自然科学基金 2008-09~2010-09 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Lili Zhang, Qi Huo, Chao Ge, Fangyu Zhao, Qingqing Zhou, Xiaoxia Chen, Hua Tian, Taoyang Chen, Haiyang Xie, Ying Cui, Ming Yao, Hong Li （通讯作者）, Jinjun Li ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma Cancer Research 2020 15;80(12):2599-2611
Zhen Song, Tengfei Liu, Jing Chen, Chao Ge, Fangyu Zhao, Miaoxin Zhu, Taoyang Chen, Ying Cui, Hua Tian, Ming Yao, Jinjun Li, Hong Li （通讯作者） HIF-1α-induced RIT1 promotes liver cancer growth and metastasis and its deficiency increases sensitivity to sorafenib Cancer Letters 2019 460 (2019):96–107
Liangyu Li, Jing Chen, Chao Ge, Fangyu Zhao, Taoyang Chen, Hua Tian, Jinjun Li, Hong Li （通讯作者） CD24 isoform a promotes cell proliferation,migration and invasion and is downregulated by EGR1 in hepatocellular carcinoma OncoTargets Ther. 2019 12:1705-1716
Hou Jianjing, Ge Chao, Cui Meiling, Liu Tengfei, Liu Xiaoqin, Tian Hua, Zhao Fangyu, Chen Taoyang, Cui Ying, Yao Ming, Li Jinjun, Li Hong （通讯作者） Pigment epithelium-derived factor promotes tumor metastasis through an interaction with laminin receptor in hepatocellular carcinomas Cell Death & Disease 2017 8(8):e2969
Cui Meiling,Sun Ji,Hou Jianjing,Fang Tao,Wang Xin,Ge Chao,Zhao Fangyu,Chen Taoyang,Xie Haiyang,Cui Ying,Yao Ming,Li Jinjun,Li Hong （通讯作者） The suppressor of cytokine signaling 2 (SOCS2) inhibits tumor metastasis in hepatocellular carcinoma Tumour Biology 2016 37(10):13521-13531
Sun Ji, Li Hong （共同第一作者）, Huo Qi, Cui Meiling, Ge Chao, Zhao Fangyu, Tian Hua, Chen Taoyang, Yao Ming, Li Jinjun The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells Oncotarget 2016 7(28):43534-43545
Gao Lin, Ge Chao, Fang Tao, Zhao Fangyu, Chen Taoyang, Yao Ming, Li Jinjun, Li Hong （通讯作者） ANGPTL2 promotes tumor metastasis in hepatocellular carcinoma Journal of Gastroenterology and Hepatology 2015 30(2):396–404
Li Hong, Cui Meiling, Chen Taoyang, Xie Haiyang, Cui Ying, Tu Hong, Chen Fuhua, Ge Chao, Li Jinjun Serum DLK1 is a potential prognostic biomarker in patients with hepatocellular carcinoma Tumor biology 2015 36:8399–8404
Fang Tao, Cui Meiling, Sun Ji, Ge Chao, Zhao Fangyu, Zhang Lin, Tian Hua, Zhang Lixing, Chen Taoyang, Jiang Guoping, Xie Haiyang, Cui Ying, Yao Ming, Li Hong （通讯作者）, Li Jinjun Orosomucoid 2 inhibits tumor metastasis and is upregulated by CCAAT/enhancer binding protein β in hepatocellular carcinomas Oncotarget 2015 6(18):16106-16119
Zhang Lin, Li Hong （共同第一作者）, Ge Chao, Li Meng, Zhao Fangyu, Hou Helei, Zhu Miaoxin, Tian Hua, Zhang Lixing, Chen Taoyang, Jiang Guoping, Xie Haiyang, Cui Ying, Yao Ming, Li Jinjun Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma Oncotarget 2014 5(21):10621-10635
Li Hong, Ge Chao, Zhao Fangyu, Yan Mingxia, Hu Chen, Jia Deshui, Tian Hua, Zhu Miaoxin, Chen Taoyang, Jiang Guoping, Xie Haiyang, Cui Ying, Gu Jianren, Tu Hong, He Xianghuo, Yao Ming, Liu Yongzhong, Li Jinjun HIF-1α-activated ANGPTL4 contributes to tumor metastasis via VCAM-1/integrin β1 signaling in human hepatocellular carcinoma Hepatology 2011 54：910-919
Hu Chen, Li Hong （共同第一作者）, Li Jinjun, Zhu Zheng, Yin Shengyong, Hao Xiangfang, Yao Ming, Zheng Shuseng, Gu Jianren Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling Carcinogenesis 2008 29：2289- 2297