导师姓名： 蔡威 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属新华医院 三级学科/
专业领域： 普外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市杨浦区控江路1665号科教楼903室
邮编： 200092 邮箱地址： caiw1978@163.com

研究方向 (点击浏览详细信息)
先天性消化道畸形基础研究、小儿肠衰竭临床与基础研究、新生儿合理营养支持、PN相关并发症的分子机制和防治研究

社会任职
上海市医学会肠外肠内营养学分会主委
中国医师学会小儿外科医师分会副会长
《World Journal of Pediatrics》副主编
《Asia Pacific Journal of Clinical Nutrion》编委
中国营养学会医用食品与营养支持分会主任委员
中国营养学会副理事长
《中华小儿外科杂志》副总编辑
《临床小儿外科杂志》副总编辑
《中华临床营养杂志》副总编辑
《Nutrition》（Pediatrics）副主编
中华医学会肠外肠内营养学分会常委
《肠外与肠内营养》副主编

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
shslczdzk05702 上海市临床重点专科建设项目—出生缺陷 上海市卫健委 2019-07~2022-06 100万元 课题负责人
** 基于长三角同质化小儿消化道畸形防治体系研究 上海市科委 2019-07~2022-06 100万元 课题负责人
2018ZDPTJD03 上海市小儿消化与营养重点实验室建设经费（2018年高水平专项） 交大医学院 2019-06~2019-11 50万元 课题负责人
基于线上线下的儿童健康管理系统 上海市经信委 2018-07~2020-06 53万元 课题负责人
17DZ** 上海市小儿消化与营养重点实验室 上海市科委 2017-04~2020-04 150万元 课题负责人
** 肠道菌群失调对早产儿肠外营养相关肝损害作用及机制研究 国家自然科学基金委员会 2017-01~2021-12 275万元 课题负责人
** 新生儿严重消化系统、神经系统及泌尿系统畸形规范化诊治的多中心临床研究 市科委 2014-07~2017-09 250万元 课题负责人
2013ZYJB0017 提高消化道畸形临床诊治疗效研究 卫计委 2014-01~2016-12 50万元 课题负责人
无 国家临床重点专科建设项目-小儿外科 国家 2013-01~2015-12 500万元 课题负责人
12GWZX0701 食品与营养卫生学-上海市公共卫生重点学科建设 卫计委 2012-01~2013-12 150万元 课题负责人
AB016 上海市小儿外科临床医学中心-上海市重中之重临床医学中心建设 卫计委 2012-01~2014-12 900万元 课题负责人
** 孕早期环境雌激素暴露对子代大鼠基因甲基化及食物过敏影响的分子机制研究 国家自然基金 2010-01~2012-12 33万元 课题负责人
** 应用抗TNF-α调控基因敲除小鼠Mdr和Mrp2防治肠外营养肝损害的实验研究 国家自然科学基金 2008-01~2010-12 29万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhiliang Wei#, Lina Lu#, Youjie Zheng, Weihui Yan, Yijing Tao, Yongtao Xiao, Wei Cai* （通讯作者）, Ying Wang* Variants in the Enteric Smooth Muscle Actin γ-2 Cause Pediatric Intestinal Pseudo-obstruction in Chinese Patients Journal of Pediatric Gastroenterology & Nutrition 2020 2020 Aug 17. doi: 10.1097/MPG.2897
Yang Wang#, Qian Jiang#, Hao Cai, Ze Xu, Wenjie Wu, Beilin Gu, Long Li*, Wei Cai* （通讯作者） Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease Aging 2020 2020 Mar 6;12(5):4379-4393
Nan Wang , Jiazheng Wang, Tian Zhang, Liufang Huang, Weihui Yan, Lina Lu, Jie Jia, Yijing Tao, Wei Cai* （通讯作者）, Ying Wang* Alterations of gut microbiota and serum bile acids are associated with parenteral nutrition-associated liver disease J Pediatr Surg 2020 2020 Jun 27;S0022-3468(20)30463-2.
Wang Y*#, Jiang Q#, Chakravarti A, Hao Cai, Ze Xu,Wenjie Wu, Beilin Gu,Long Li*, Wei Cai* （通讯作者） MicroRNA-4516-mediated regulation of MAPK10 relies on 3'UTR cis-acting variants and contributes to the altered risk of Hirschsprung disease Journal of Medical Genetics 2020 2020;57:634–642
Tian Zhang#, Yang Liu#, Jun-Kai Yan*, Wei Cai* （通讯作者） Early downregulation of P-glycoprotein facilitates bacterial attachment to intestinal epithelial cells and thereby triggers barrier dysfunction in a rodent model of total parenteral nutrition FASEB Journal 2020 2020 Mar;34(3):4670-4683
Qiu Y, Sun S, Yu X, Zhou J, Cai W* （通讯作者）, Qian L* Carboxyl ester lipase is highly conserved in utilizing maternal supplied lipids during early development of zebrafish and human Biochim Biophys Acta Mol Cell Biol Lipids 2020 2020 Feb 12;1865(6):158663
Xian-Xian Yu#, Xun Chu#*, Wen-jie Wu, Zhi-Liang Wei, Huan-Lei Song, Mei-Rong Bai, Yan-Jiao Lu, Bei-Lin Gu, Yi-Ming Gong, Wei Cai* （通讯作者） Common variation of the NSD1 gene is associated with susceptibility to Hirschsprung's disease in Chinese Han population Pediatric Research 2020 2020 May 7. doi: 10.1038/s41390-020-0933-3
Ying Wang#, Shanshan Chen#, Weihui Yan, Lina Lu, Yijing Tao, Yongtao Xiao*, Wei Cai* （通讯作者） Congenital Short-Bowel Syndrome: Clinical and Genetic Presentation in China J Parenter Enteral Nutr 2020 DOI: 10.1002/jpen.1974 wileyonlinelibrary.com
Bai MR#, Niu WB#, Zhou Y#, Gong YM, Lu YJ, Yu XX, Wei ZL, Wu W, Song HL, Yu WW, Gu BL, Cai W* （通讯作者）, Chu X* Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility Aging 2020 2020 Apr 21;12(8):7163-7182
Jie Jia, Pengcheng Xun, Xinling Wang, Ka He, Qingya Tang, Tian Zhang ,Ying Wang, Wenjing Tang, Lina Lu, Weihui Yan, Weiping Wang, Tianyi Hu, Wei Cai* （通讯作者） Impact of Postnatal Antibiotics and Parenteral Nutrition on the Gut Microbiota in Preterm Infants during Early Life Journal of Parenteral and Enteral Nutrition 2020 2020 May;44(4):639-654
Zhiliang Wei#, Xianxian Yu#, Wenjie Wu, Meirong Bai, Yanjiao Lu, Huanlei Song, Yiming Gong, Beilin Gu, Xun Chu*, Wei Cai* （通讯作者） Common variants of NRG1 and ITGB4 confer risk of Hirschsprung disease in Han Chinese population Journal of Pediatric Surgery 2020 2020 Apr 21;S0022-3468(20)30268-2
Kefeng Yang#, Jie Zhu#, Jiang Wu, Yan Zhong, Xiuhua Shen, Brawnie Petrov, Wei Cai* （通讯作者） Maternal Vitamin D Deficiency Increases Intestinal Permeability and Programs Wnt/β‐Catenin Pathway in BALB/C Mice JPEN J Parenter Enteral Nutr 2020 2020 https://doi.org/10.1002/jpen.1820
Wei-Bo Niu, Mei-Rong Bai, Huan-Lei Song, Yan-Jiao Lu, Wen-Jie Wu,Yi-Ming Gong, Xian-Xian Yu, Zhi-Liang Wei, Wen-Wen Yu, Bei-Lin Gu,Wei Cai* （通讯作者）,Xun Chu* Association study of genetic variants on PLD1, 3p24.1 and 10q11.21 regions with HSCR in the Chinese population Frontiers in Genetics 2020 2020;11:738
Li-Na Dai, Jun-Kai Yan, Tian Zhang, Wei Cai* （通讯作者）, Wei-Hui Yan* Butyrate promotes the adaptation of intestinal smooth muscle cells through the yes-associated protein (YAP) pathway in a rat model of short bowel syndrome American Journal of Translational Research 2019 11(1):453-462
Yan JK, Zhang T, Dai LN, Gu BL, Zhu J, Yan WH, Cai W* （通讯作者） Wang Y*. CELF1/p53 axis: a sustained anti-proliferative signal leading to villus atrophy under total parenteral nutrition FASEB Journal 2019 33(3):3378-3391
Cao Y, Xiao Y, Zhou K, Yan J, Wang P, Yan W, Cai W* （通讯作者） FXR agonist GW4064 improves the liver and intestinal pathology and alters bile acid metabolism in rats undergoing small intestinal resection American Journal of Physiology-Gastrointestinal and Liver Physiology 2019 317(2):G108-G115
Tian Zhang,Ying Wang,Weihui Yan,Lina Lu,Yijing Tao,Jie Jia,Wei Cai* （通讯作者） Microbial alteration of small bowel stoma effluents and colonic feces in infants with short bowel syndrome Journal of Pediatric Surgery 2019 pii: S0022-3468(19)30511-1. doi: 10.1016/j.jpedsurg.2019.08.004. [Epub ahead of print]
Zhang T, Yan JK, Wang N, Dai LN, Wang Y, Cai W* （通讯作者） Autophagy may protect against parenteral nutrition-associated liver disease by suppressing endoplasmic reticulum stress Journal of Parenteral and Enteral Nutrition 2019 43(1):96-106
Cui X, Wang B, Wu Y, Xie L, Xun P, Tang Q, Cai W* （通讯作者）, Shen X* Vegetarians have a lower fasting insulin level and higher insulin sensitivity than matched omnivores: A cross-sectional study Nutrition Metabolism and Cardiovascular Diseases 2019 29(5):467-473
Lu W, Xiao YT, Huang JH, Lu LN, Tao YQ, Yan WH, Cao Y, Cai W* （通讯作者） Causes and prognosis of chronic intestinal pseudo-obstruction in 48 subjects Medicine 2018 97(36):e12150
Yan JK, Zhu J, Gong ZZ, Wen J, Xiao YT, Zhang T, Cai W*. （通讯作者） Supplementary choline attenuates olive oil lipid emulsion-induced enterocyte apoptosis through suppression of CELF1/AIF pathway. Journal of Cellular and Molecular Medicine 2018 22(3):1562-1573
Gong ZZ, Zhao SN, Zhou JF, Yan JK, Wang LY, Du XX, Li H, Chen YW, Cai W* （通讯作者）, Wu J* Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production Molecular Immunology 2018 104:11-19
Shen X, Tang W, Yu Z, Cai W* （通讯作者） The history and development of registered dietitian accreditation systems in China and other comparable countries Nutrition Research 2018 PMID: **. Epub 2018/08/06
Yang Y, Zheng T, Zhou J, Song HL, Cai W* （通讯作者）,Qian LX* Bile salt dependent lipase promotes intestinal adaptation in rats with massive small bowel resection Bioscience Reports 2018 38(3)
Wu J, Zhong Y, Shen XH, Yang KF*, Cai W*. （通讯作者） Maternal and early-life vitamin D deficiency enhances allergic reaction in an ovalbumin-sensitized BALB/c mouse model. Food & Nutrition Research 2018 62:1401
Xiao YT, Zhou Y, Lu Ying, Zhou KJ, Cai Wei*. （通讯作者） PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver. Cell Death and Disease 2018 9:160
Wei Cai , Phillip C. Calder, Maria F.Cury-Boaventura , Elisabeth De Waele,Julie Jakubowski* and Gary Zaloga. Biological and clinical aspects of an oliveoil-based lipid emulsion-a review. Nutrients 2018 10,776
Wu J, Yang KF, Wu WJ, Tang QY, Zhong Y, Gabriele Gross, Tim T. Lambers, Eric A.F.van Tol, Cai W*. （通讯作者） Soluble Mediators From Lactobacillus rhamnosus Gorbach-Goldin Support Intestinal Barrier Function in Rats After Massive Small-Bowel Resection. Journal of Parenteral and Enteral Nutrition 2018 42(6):1026-1034
Wang Y, Yan WH, Wang J, Zhou Y, Chen J, Gu BL, Cai W*. （通讯作者） Common genetic variants in GAL, GAP43 and NRSN1 and interaction networks confer susceptibility to Hirschsprung disease. Journal of Cellular and Molecular Medicine 2018 22:3377-87
Zhang T, Wang N, Yan WH, Lu LN, Tao YJ, Li F, Wang Y*, Cai W* （通讯作者） Effect of a fish oil-based lipid emulsion on intestinal failure-associated liver disease in children European Journal of Clinical Nutrition 2018 72(10):1364-1372
Yan JK,Yan WH,Cai W*. （通讯作者） Fish oil-derived lipid emulsion induces RIP1-dependent and caspase 8-licensed necroptosis in IEC-6 cells through overproduction of reactive oxygen species. Lipids in Health and Disease 2018 17(1):148
Xiao Y, Zhou Y, Zhou K, Lu Y, Yan W, Cai W* （通讯作者）,Wang Y* Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling Experimental & Molecular Medicine 2018 50(12):155
Dai LN, Yan JK, Xiao YT, Wen J, Zhang T, Zhou KJ, Wang Y , Cai W*. （通讯作者） Butyrate stimulates the growth of human intestinal smooth muscle cells by activation of yes-associated protein. Journal of cellular Physiology 2018 233(4):3119-3128
Zhao SN, Gong ZZ, Du XX, Tian CY, Wang LY, Zhou JF, Xu CF, Chen YW, Cai W* （通讯作者）, Wu J* Deoxycholic acid-mediated sphingosine-1-phosphate receptor 2 signaling exacerbates DSS-induced colitis through promoting cathepsin B release Journal of Immunology Research 2018 **
Lu LN, Mao XM, Sheng JY, Huang JH, Wang Y, Tang QY, Cai W*. （通讯作者） Development and validation of a pediatric nutritional screening score (PNSS) for hospitalized children Asia Pacific Journal of Clinical Nutrition 2018 27(1):65-71
Wu S, Qian LX, Huang L, Sun XM, Su HY, Deepanjali D. Gurav, Jiang MW, Cai W* （通讯作者）, Qian K*. A plasmonic mass spectrometry approach for detection of small nutrients and toxins. Nano-Micro Letters 2018 10:52
Xiao YT, Zhou Y, Lu Ying, Zhou KJ, Cai Wei* （通讯作者） PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver Cell Death & Disease 2018 9:160
Xiao YT, Wang J, Yan WH, Zhou KJ, Cao Y, Cai W*. （通讯作者） p38αMAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure. Cell Death and Disease 2017 8(10):e3110
Feng HX, Xun PC, Pike K, Wills AK, Chawes BL, Bisgaard H, Cai W, Wan YP, He K. In utero exposure to 25-hydroxyvitamin D and risk of childhood asthma, wheeze, and respiratory tract infections: A meta-analysis of birth cohort studies. Journal of Allergy and Clinical Immunology 2017 139(5):1508-1517
Wang PL, Wang J, Zhou Y, Zhou KJ, Wen J, Cai W*. （通讯作者） Expression of programmed death-1 and its ligands in the liver of biliary atresia. World Journal of Pediatrics 2017 13
Wen J, Yu Q, Chen HY, Chen NN, Huang SR, Cai W*. （通讯作者） Peripherally inserted central venous catheter-associated complications exert negative effects on body weight gain in neonatal intensive care units. Asia Pacific Journal of Clinical Nutrition 2017 26(1):1-5
Wang Y , Veremeyko T, Wong AH, El Fatimy R, Wei Z, Cai W, Krichevsky AM. Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease. Neurobiol Aging 2017 51:156-66
Wang J, Zhang MZ, Pan WH, Wu WJ, Yan WB, Cai W*. （通讯作者） Management of recurrent tracheoesophageal fistula after esophageal atresia and follow-up. Disease of the Esophagus 2017 30(9):1-8
Wu J, Xun PC, Tang QY, Cai W*, He K*. （通讯作者） Circulating magnesium levels and incidence of coronary heart diseases,hypertension, and type 2 diabetes mellitus:a meta-analysis of prospective cohort studies. Nutrition Journal 2017 16(1):60.
Lu LP,Wan YP,Xun PC,Zhou KJ,Chen C,Cheng SY,Zhang MZ,Wu CH,Lin WW,Jiang Y,Feng HX,Wang JL,He K,Cai W*. （通讯作者） Serum bile acid level and fatty acid composition in Chinese children with non-alcoholic fatty liver disease. Journal of Digestive Diseases 2017 18(8):461-471.
Yan JK, Gong ZZ, Zhang T, Cai W*. （通讯作者） Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells. Biochemical and Biophysical Research Communications 2017 482:791-795
Xiao YT, Yan WH, Cao Y, Yan JK, Cai W*. （通讯作者） P38 MAPK pharmacological inhibitor SB203580 alleviates total parenteral nutrition-induced loss of intestinal barrier function but promotes hepatocyte lipoapoptosis. Cellular Physiology and Biochemistry 2017 41:623-634
Zhang MZ, Xun PC, He K, Cai W*. （通讯作者） Adjuvant steroid treatment following Kasai portoenterostomy and clinical outcomes of biliary atresia patients: an updated meta-analysis. World Journal of Pediatrics 2017 13 (1):20-26
Yan JK, Zhu J, Gong ZZ, Wen J, Xiao YT, Zhang T, Cai W*. （通讯作者） Olive oil-supplemented lipid emulsion induces CELF1 expression and promotes apoptosis in Caco-2 Cells. Cellular Physiology and Biochemistry 2017 41:711-721
Yan WH, Hong L, Wang Y, Feng Y, Lu LN, Tao YJ, Wu J, Ruan HJ, Tang QY, Cai W*. （通讯作者） Retrospective dual-center study of parenteral nutrition–associated cholestasis in premature neonates: 15 years’ experience Nutrition in Clinical Practice 2017 32(3):407-13
Wang PL,Wang Y, Lu LN,Yan WH,Tao YJ,Zhou KJ,Jia J,Cai W*. （通讯作者） Alterations in intestinal microbiota relate to intestinal failure-associated liver disease and central line infections. Journal of Pediatric Surgery 2017 52(8):1318-1326
Yan JK, Zhou KJ, Huang JH, Wu QQ, Zhang T, Wang CC, Cai W*. （通讯作者） Urinary glutamine/glutamate ratio as a potential biomarker of pediatric chronic intestinal pseudo-obstruction. Orphanet Journal of Rare Diseases 2017 12:62
Cheng SY,Wang J,Pan WH,Yan WB,Shi J,Guan WB,Wang Y,Cai W*. （通讯作者） Pathologically assessed grade of Hirschsprung-associated enterocolitis in resected colon in children with Hirschsprung's disease predicts postoperative bowel function. Journal of Pediatric Surgery 2017 52(11):1776-1781
Gong ZZ, Zhou JF, Zhao SN, Tian CY, Wang PL, Xu CF, Chen YW, Cai W* （通讯作者）, Wu J*. Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis. Oncotarget 2016 7(51): 83951–83963
Qian LX, Song HL, Cai W*. （通讯作者） Determination of Bifidobacterium and Lactobacillus in breast milk of healthy women by digital PCR. Beneficial Microbes 2016 7(4):559-569
Panliang Wang, Pengcheng Xun, Ka He, Wei Cai （通讯作者） Comparion of liver transplatation outcomes in biliary atresia patients with and without prior portoenterostomy: a meta-ananlysis. Digestive and Liver Diease 2016 48(4):347-352
Dai LN, Chen YW, Yan WH, Lu LN, Tao YJ, Cai W*. （通讯作者） Hereditary pancreatitis of 3 Chinese children: Case report and literature review. Medicine 2016 95(36):e4604
Xiao YT, Wang J, Lu W, Cao Y, Cai W*. （通讯作者） Downregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChE. Cell Death & Disease 2016 7(12): e2521
Zhao SN, Gong ZZ, Zhou JF, Tian CY, Gao YH, Xu CF, Chen YW, Cai W* （通讯作者）, Wu J*. Deoxycholic acid triggers NLRP3 inflammasome activation and aggravates DSS-induced colitis in mice. Frontiers in Immunology 2016 7:536
Ying Wang, Yi Feng, Li-Na Lu, Wei-Ping Wang, Zhen-Juan He, Li-Juan Xie,Li Hong, Qing-Ya Tang, Wei Cai* （通讯作者） The effects of different lipid emulsions on the lipid profile, fatty acid composition, and antioxidant capacity of preterm infants: A doubleblind,randomized clinical trial Clinical Nutrition 2016 35(5):1023-1031
Lu W, Xiao YT, Huang JH, Tao YJ, Yan WH, Lu LN, Cao Y, Cai W*. （通讯作者） Mutation in actin gamma-2 responsible for megacystis microcolon intestinal hypoperistalsis syndrome in 4 Chinese patients. Journal of Pediatric Gastroenterology and Nutrition 2016 63(6):624-626
Cao Y, Yan WH, Lu LN, Tao YJ, Lu W, Chen YW, Tang QY, Cai W*. （通讯作者） Parenteral nutrition combined with rice soup can be a safe and effective intervention for congenital chylous ascites. Asia Pacific Journal of Clinical Nutrition 2016 25(3):631-635
Wang Y, Wang J, Zhou Y, Wei ZY, Xiao YT, Zhou KJ, Wen J, Yan JK, Cai W*. （通讯作者） Contribution of common variants in GABRG2, RELN and NRG3 and interaction networks to the risk of Hirschsprung disease. Cellular Physiology and Biochemistry 2016 40(3-4):509-526
Yongtao Xiao, Weihui Yan, Kejun Zhou, Yi Cao, Wei Cai （通讯作者） Glucocorticoid treatment alters systemic bile acid homeostasis by regulating the biosynthesis and transprt of bile salts. Digestive and Liver Diease 2016 48(7):771-779
L Lu, P Xun, Y Wan, K He, W Cai* （通讯作者） Long-term association between dairy consumption and risk fo childhood obesity : a systematic review and meta-analysis of prospective cohort studies. European Journal of Clinical Nutrition 2016 70(4):414-423
Yan JK, Zhu J, Gu BL, Yan WH, Xiao YT, Zhou KJ, Wen J, Wang Y, Cai W*. （通讯作者） Soybean oil-based lipid emulsion increases intestinal permeability of lipopolysaccharide in Caco-2 cells by downregulation of P-Glycoprotein via ERK-FOXO 3a pathway. Cellular Physiology and Biochemistry 2016 39(4):1581-1594
Yong-Tao Xiao, Wei-Hui Yan, Yi Cao, Jun-Kai Yan, Wei Cai* （通讯作者） Neutralization of IL-6 and TNF-αameliorates intestinal perneability in DSS-induced colitis. Cytokine 2016 83:189-192
Zhou KJ, Xie GX, Wen J, Wang J, Pan WH, Zhou Y, Xiao YT, Wang Y, Jia W*, Cai W*. （通讯作者） Histamine is correlated with liver fibrosis in biliary atresia. Digestive and Liver Disease 2016 48(8):921-926
Xiao YT, Cao Y, Zhou KJ, Lu LN, Cai W*. （通讯作者） Altered systemic bile acid homeostasis contributes to liver disease in pediatric patients with intestinal failure. Scientific Reports 2016 6:39264
Wang Y,Zhou KJ,Tang QY,Hong L,Feng Y,Lu LN,Wang WP,Cai W （通讯作者）, Effect of an Olive Oil- Based Lipid Emulsion Compared With a Soybean Oil- Based Lipid Emulsion on Liver Chemistry and Bile Acid Composition in Preterm Infants Receiving Parenteral Nutrition: A Double-Blind, Randomized Trial. J Parenter Enteral Nutr 2016 40(6):842-850
Z. Gong, J. Zhou, H. Li, Y. Gao, C. Xu, S. Zhao, Y. Chen, W. Cai and J. Wu （通讯作者） Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Mol Nutr Food Res 2015 59:2132-2142
Kejun Zhou, Jun Wang, Guoxiang Xie,Ying Zhou, Weihui Yan, Weihua Pan, Yanran Che, Ting Zhang, Linda Wong, Sandi Kwee, Yongtao Xiao, Jie Wen, Wei Cai* （通讯作者）, Wei Jia Distinct plasma bile acid profiles of biliary atresia and neonatal hepatitis syndrome. J Proteome Res. 2015 14(11):4844-4850
Xiao Y, Yan W, Lu L, Wang Y, Lu W, Cao Y, Cai W* （通讯作者） p38/p53/miR-200a-3p feedback loop promotes oxidative stress-mediated liver cell death. Cell Cycle 2015 14(10) :1548-1558
Bei F,Jia J,Jia YQ,Sun JH,Liang F,Yu ZY,Cai W* （通讯作者） Long-term effect of early postnatal overnutrition on insulin resistance and serum fatty acid profiles in male rats. Lipids Health Dis. 2015 14(1):96
Xiao Y,Wang J,Yan W,Zhou Y,Chen Y,Zhou K,Wen J,Wang Y,Cai W （通讯作者）, Dysregulated miR-124 and miR-200 expression contribute to cholangiocyte proliferation in the cholestatic liver by targeting IL-6/STAT3 signalling J Hepatol 2015 62(4):889-896
Xiao Y,Zhou Y,Chen Y,Zhou K,Wen J,Wang Y,Wang J,Cai W （通讯作者）, The expression of epithelial- mesenchymal transition- related proteins in biliary epithelial cells is associated with liver fibrosis in biliary atresia. Pediatr Res. 2015 77(2):310-315
Wenjing Tang, Huanlei Song, Wei Cai* （通讯作者）, Xiuhua Shen Real time monitoring of inhibition of adipogenesis and angiogenesis by (-)-Epigallocatechin-3-gallate in 3T3-L1 adipocytes and human umbilical vein endothelial cells. Nutrients 2015 7(10):8871-8886
Zhou K,Xie G,Wang J,Zhao A,Liu J,Su M,Ni Y,Zhou Y,Pan W,Che Y,Zhang T,Xiao Y,Wang Y,Wen J,Jia W,Cai W （通讯作者）, Metabonomics reveals metabolite changes in biliary atresia infants. J Proteome Res. 2015 14(6):2569-2574
Wen J,Xiao Y,Wang J,Pan W,Zhou Y,Zhang X,Guan W,Chen Y,Zhou K,Wang Y,Shi B,Zhou X,Yuan Z,Cai W （通讯作者）, Low doses of CMV induce autoimmune- mediated and inflammatory responses in bile duct epithelia of regulatory T cell- depleted neonatal mice. Lab Invest 2015 95(2):180-192
Jie Liu, Kaimeng Kong, Yexuan Tao,Wei Cai （通讯作者） Optimal timing for introducing enteral nutrition in the neonatal intensive care unit Asia Pac J Clin Nutr 2015 24(2):219-226
Wu J,Chen J,Wu W,Shi J,Zhong Y,van Tol EA,Tang Q,Cai W （通讯作者）, Enteral supplementation of bovine lactoferrin improves gut barrier function in rats after massive bowel resection. Br J Nutr. 2014 112(4) :486-492
Chen ZH,Zhang YC,Jiang WF,Yang C,Zou GM,Kong Y,Cai W （通讯作者）, Characterization of interstitial Cajal progenitors cells and their changes in Hirschsprung's disease. PLoS One. 2014 9(1) :e86100
Du L, Pan WH, Cai W* （通讯作者）, Wang J, Wu YM, Shi CR. Delivery room surgery: an applicable therapeutic strategy for gastroschisis in developing countries. World Journal of Pediatrics 2014 10(1):69-73
Yan W,Wang Y,Xiao Y,Wen J,Wu J,Du L,Cai W （通讯作者）, Palmitate induces TRB3 expression and promotes apoptosis in human liver cells. Cell Physiol Biochem. 2014 33(3) :823-834
Zhang C, Du L, Cai W* （通讯作者）, Wu Y, Lv F. Isolated hepatobiliary cryptococcosis manifesting as obstructive jaundice in an immunocompetent child: case report and review of the literature. Eur J Pediatr 2014 173(12):1569-1572
Xiao Y,Wang J,Chen Y,Zhou K,Wen J,Wang Y,Zhou Y,Pan W,Cai W （通讯作者）, Up-regulation of miR-200b in biliary atresia patients accelerates proliferation and migration of hepatic stallate cells by activating PI3K/Akt signaling. Cell Signal. 2014 26(5):925-932
Wang J, Du L, Cai W* （通讯作者）, Pan WH, Yan WB. Prolonged feeding difficulties after surgical correction of intestinal atresia: a 13-year experience. Journal of Pediatric Surgery, 2014 49(11):1593-1597
Mingshun Zhang, Shuna Sun, Ning Tang, Wei Cai* and Linxi Qian*. （通讯作者） Oral administration of alkylglycerols differentially modulates high-fat diet induced obesity and insulin resistance in mice. Evid-Based Compl Alt 2013 834027
Wang Y, Wang J, Pan W, Zhou Y, Xiao Y, Zhou K, Wen J, Yu T, Cai W*. （通讯作者） Common Genetic Variations in Patched1 (PTCH1) Gene and Risk of Hirschsprung Disease in the Han Chinese Population. PLos One 2013 8(9):e75407
Feng Y, Zhao LZ, Hong L, Shan C, Shi W, Cai W*. （通讯作者） Alteration in methylation pattern of GATA-4 promoter region in vitamin A-deficient offspring's heart. J Nutr Biochem 2013 24(7):1373-1380
Wang Y, Cai W* （通讯作者）, Tao YX, Tang QY, Feng Y, Wu J. Glutamine supplementation in preterm infants receiving parenteral nutrition leads to an early improvement in liver function. Asia Pac J Clin Nutr 2013 22(4):530-536
Chen Y, Xiao Y, Ge W, Zhou K, Wen J, Yan W, Wang Y, Wang B, Qu C, Wu J, Xu L, Cai W*. （通讯作者） miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells. Cell Death Dis 2013 4:e541
Chen J, Du L, Xiao Y, Cai W*. （通讯作者） Disruption of interstitial cells of Cajal networks after massive small bowel resection. World J Gastroentero 2013 19(22):3415-3422
Wu J, Huang C, Xiao H, Tang Q, Cai W*. （通讯作者） Weight loss and resting energy expenditure in male patients with newly diagnosed esophageal cancer. Nutrition 2013 29(11-12):1310-1314
Bei F, Sun JH, Yu YG, Jia J, Zheng ZJ, Fu QH, Cai W*. （通讯作者） Two Novel Isovaleryl-CoA Dehydrogenase Gene Mutations in a Chinese Infant. Gene 2013 524(2):396-400
Yang KF, Cai W （通讯作者）, Xu JL, Shi W Maternal high-fat diet programs Wnt genes through histone modification in the liver of neonatal rats Mol Endocrinol 2012 49(2):107-114
Li J, Gong YM, Wu J, Wu WJ, Cai W （通讯作者） Anti-tumor necrosis factor-α monoclonal antibody alleviates parenteralnutrition-associated liver disease in mice JPEN J Parenter Enteral Nutr 2012 36(2):219-225
FENG Y, YU YM, YIN MZ, HONG L, CAI W （通讯作者） Ectopic expression of retinoic acid receptors and change of myocardial structure in the offspring heart with vitamin A deficiency J Nutr Sci Vitaminol 2012 58(5):309-318
Chen J, Wen J, Cai W*. （通讯作者） Smooth muscle adaptation and recovery of contractility after massive small bowel resection in rats. Experimental Biology and Medicine 2012 237(5):578-584
Qian L, Wang B, Tang N, Zhang W, Cai W （通讯作者） Polymorphisms of SLC30A2 and selected perinatal factors associated with low milk zinc in Chinese breastfeeding women Early Hum Dev 2012 88(8):663-668
Kejun Zhou,Na Lin,Yongtao Xiao,Yang Wang,Jie Wen,Gang-Ming Zou,XueFan Gu,Wei Cai （通讯作者） Elevated Bile Acids in Newborns with Biliary Atresia (BA) PLOS one 2012 7(11):e49270-49270
Yang KF, Shen XH, Cai W （通讯作者） Prenatal and early postnatal exposure to high-saturated-fat diet represses Wnt signaling and myogenic genes in offspring rats Exp Biol Med 2012 237(8):912-918