导师姓名： 龚伟 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属新华医院 三级学科/
专业领域： 普外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： **@163.com
邮编： 200092 邮箱地址： **@163.com

研究方向 (点击浏览详细信息)
胆道肿瘤的临床和基础

社会任职
中华医学会外科学分会全国中青年委员
中华实验外科杂志专家委员会委员
中国医师协会胆道外科委员会委员
上海市医学会外科学会胆道学组委员
Journal of Digestive Disease, PlosOne等杂志审稿专家
中华肝胆外科杂志通讯编委
国家自然基金评议专家
中华医学会外科学分会胆道学组委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** IMP3介导的lncRNA-LEMD1促进胆囊癌细胞侵袭转移的功能及机制研究 国家自然基金 2020-01~2023-12 55万元 课题负责人
TT-00420 多激酶抑制剂TT-00420的临床与多中心篮式实验 国家重大科技专项子项目 2019-01~2020-12 41.6万元 课题负责人
** MALAT1通过负调控 miR-31促进胆囊癌发生发展的分子机制研究 国家自然基金 2017-01~2020-01 56万元 课题负责人
** 上海交通大学医学院高原高峰计划 上海交大医学院 2015-10~2018-10 100万元 课题负责人
124119a0600 胆囊癌中微小RNA（miRNA）对化疗敏感性调控的研究 上海市科委 2012-10~2015-09 20万元 课题负责人
** 抑癌基因ING1在表观遗传学调控中的作用 上海市卫生局 2010-12~2012-12 4万元 课题负责人
** 胆囊癌长链非编码RNA的功能及其相关分子机制研究 国家自然基金 2010-12~2012-12 28万元 课题参与人
粘液瘤病毒对胃癌的治疗作用及其机制研究 上海市科委国际合作 2010-06~2012-06 20万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Shilei Liu, Bingfeng Chu, Chen Cai, Xiangsong Wu, Wenyan Yao, Ziyou Wu, Ziyi Yang, Fengnan Li, Yingbin Liu, Ping Dong, Wei Gong （通讯作者） DGCR5 Promotes GallbladderCancer by Sponging MiR-3619-5p via MEK/ERK1/2 and JNK/p38 MAPK Pathways J Cancer. 2020 2020; 11(18): 5466–5477.
Shilei Liu, Fengnan Li, Lijia Pan, Ziyi Yang, Yijun Shu, Wenjie Lv, Ping Dong, Wei Gong(龚伟) （通讯作者） BRD4 inhibitor and histone deacetylase inhibitor synergistically inhibit the proliferation of gallbladder cancer in vitro and in vivo Cancer Science 2019 00:1-14
Fei Zhang, Qiang Ma1,Zihang Xu3, Haibin Liang,Huaifeng Li, Yuanyuan Ye, Shanshan Xiang,Yijian Zhang, Lin Jiang, Yunping Hu, Zheng Wang, Xuefeng Wang, Yong Zhang, Wei Gong （通讯作者）,Yingbin Liu1 Dihydroartemisinin inhibits TCTPdependent metastasis in gallbladder cancer Journal of Experimental & Clinical Cancer Research 2017 DOI 10.1186/s13046-017-0531-3
Maolan Li1, Wei Chen1, Hongchen Zhang, Yong Zhang, Fayong Ke, Xiangsong Wu, Yijian Zhang, Mingzhe Weng, Yingbin Liu1, Wei Gong （通讯作者） MiR-31 regulates the cisplatin resistance by targeting Src in gallbladder cancer Oncotarget 2016 Vol. 7,,: 83060-83070
Hongchen Zhang ,Zhizhen Li , Bingfeng Chu , Fei Zhang, Yijian Zhang, Fayong Ke, Yuanyuan Chen, Yi Xu, Shibo Liu, Shuai Zhao, Haibin Liang, Mingzhe Weng, Xiangsong Wu, Maolan Li, Wenguang Wu, Zhiwei Quan, Yingbin Liu, Yong Zhang, Wei Gong(龚伟) （通讯作者） Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma. Tumor Biology 2016 2006
Fa-Yong Ke, Xiang-Song Wu, Yong Zhang, Hong-Cheng Zhang, Ming-Zhe Weng, Ying-Bin Liu, Christopher Wolfgang, Wei Gong(龚伟) （通讯作者） Comparison of postoperative complications between internal and external pancreatic duct stenting during pancreaticoduodenectomy: a meta-analysis. Chinese Jouranl of Cancer Research 2015 27(4):397-407
Hongchen Zhang, Jian Zhu, Fayong Ke, Mingzhe Weng, Xiangsong Wu, Maolan Li, Zhiwei Quan, Yingbin Liu, Yong Zhang, and Wei Gong(龚伟)* （通讯作者） Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis Biomed Research International 2015 2015
Tian-Yu Liu,# Wei Gong （共同第一作者）,# Zhu-Jun Tan,# Wei Lu, Xiang-Song Wu, Hao Weng,Qian Ding,Yi-Jun Shu,Run-Fa Bao,Yang Cao, Xu-An Wang,Fei Zhang,Huai-Feng Li,Shan-Shan Xiang,Lin Jiang, Yun-ping Hu, Jia-Sheng Mu,Mao-Lan Li,Wen-Guang Wu,Bai-Yong Shen, Li-Xin Jiang, and Ying-Bin Liu* Baicalein inhibits progression of gallbladder cancer cells by downregulating ZFX. PLoS One 2015 10(1): e**.
Mingzhe Weng, Wei Gong(龚伟) （共同第一作者）, Mingzhe Ma, Bingfeng Chu, Yiyu Qin, Mingdi Zhang, Xueqing Lun,Grant McFadden, Peter Forsyth, Yong Yang and Zhiwei Quan Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo. Molecular Cancer 2014 13(1):1-15
龚伟,刘颖斌 胰腺囊性占位的诊断和处理 肝胆外科杂志 2013 21(4):253-255
龚伟 张生来 杨勇 王雪峰 储冰峰 全志伟 刘颖斌 张勇 毕建威 方国恩 （共同第一作者） p33ING1b蛋白在胆囊癌中表达的研究 肝胆外科杂志 2011 12:541-457.
Zhou D, Zhang Y, Gong W(龚伟), Mohamed SO, Ogbomo H, Wang X, Liu Y, Quan Z. Are Helicobacter pylori and other Helicobacter species infection asso ciated with human biliary lithiasis? A meta-analysis. Plos one 2011 6(11):e27390.
龚伟 刘颖斌 （通讯作者） 胰腺假性囊肿治疗的选择 肝胆外科杂志 2011 42:49-250
龚伟 刘颖斌 （通讯作者） 先天性胆总管囊肿与胆管癌 肝胆外科杂志 2010 5:333-334
Gong W(龚伟), Russell M, Suzuki K, Riabowol K. Subcellular Targeting of p33ING1b by Phosphorylation-Dependent 14-3-3 Binding Regulates p21WAF1 Ex pressions. Mol Cell Bio. 2006 26(8):2947-54.
Russell M, Berardi P, Gong W(龚伟), Riabowol K. Grow-ING, Age-ING and Di e-ING: ING proteins link cancer, senescence and apoptosis. Experimental Cell Research. 2006 312:6951–6961
Gong W(龚伟) （共同第一作者）, Qin YY, Li SG, Quan ZW, Li JY, Zhuang PY, Wan ZW. Zhonghua Yi Xue Za Zhi. Somatostatin enhanced anti-tumor effect of doxorubicin on gallbladder cancer cells through the regulation of intracellular drug co ncentration. 中华医学杂志 19;90(38):2718-22.
Chivers JE, Gong W(龚伟) （共同第一作者）, King EM, Seybold J, Mak JC, Donnelly L E, Holde n NS, Newton R. Analysis of the dissociated steroid RU24858 does not excl ude a role for inducible genes in the anti-inflammatory actions of glucoc orticoids. Mol Pharmacol. 70(6):2084-95.
Qin Y, Zhang S, Gong W(龚伟), Li J, Jia J, Quan Z. Adenovirus-mediated gene transfer of TFPI-2 inhibits gallbladder carcinoma growth in vitro and in vivo. Cancer Sci 10：1349-7006
Mingzhe Weng., Yong Zhang., Di Zhou, Yong Yang, Zhaohui Tang, Mingning Zhao, Zhiwei Quan*,Wei Gong(龚伟)* Radiofrequency Ablation versus Resection for ColorectalCancer Liver Metastases: A Meta-Analysis Plos One 7(9): e45493-45501
Jia J, Li S, Gong W(龚伟), Ding J, Fang C, Quan Z. mda-7/IL-24 induces a poptosis in human GBC-SD gallbladder carcinoma cells via mitochondrial a poptotic pathway. Oncol Rep. 25(1):195-201.
Gong, W(龚伟), Suzuki K, Russell M, Riabowol K. Function of the ING family of PHD proteins in cancer. Int J Biochem Cell Biol. 37(5):1054-1065.
Suzuki K, Boland D, Gong W(龚伟), Riabowol K. Adenovirus-mediated gene transfer of TFPI-Domain recognition of the ING1 tumor suppressor by a panel of monoclonal antibodies. Hybridoma 30(3):239-45