导师姓名： 蒋盛旦 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属新华医院 三级学科/
专业领域： 骨外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市杨浦区控江路1665号
邮编： 200092 邮箱地址： jiangsd@126.com

研究方向 (点击浏览详细信息)
脊柱外科基础与临床

社会任职
新华医院骨科行政副主任，支部书记

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
XH2476 椎体成型术与关节突阻滞在骨质诉讼性椎体骨折中的疗效比较 上海交通大学医学院 2018-10~2021-09 100万元 课题负责人
** 氧化应激诱导的线粒体自噬在椎间盘退变中的作用及机制研究 国家自然科学基金面上项目 2017-01~2020-12 57万元 课题负责人
** 缺氧对椎间盘代谢的影响及其机制研究 国家自然科学基金 2011-01~2013-12 20万元 课题负责人
XYQ** 缺氧信号在椎间盘退变病理机制中的作用 卫生局 2011-01~2013-12 60万元 课题负责人
2008SG21 谷氨酸及受体在脊髓损伤后骨质疏松中的作用 市教委 2008-09~2010-08 6万元 课题负责人
08QA** 谷氨酸及其受体在脊髓损伤后骨质疏松中的作用 上海市科委,启明星 2008-07~2010-07 15万元 课题负责人
2007XJ026 脊髓损伤后骨质疏松的分子和信号传导机制 医学院 2008-01~2009-12 5万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Liu T, Li B, Zheng XF, Jiang SD, Zhou ZZ, Xu WN, Zheng HL, Wang CD, Zhang XL, Jiang LS Chordin-Like 1 Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells Through Enhancing BMP4-SMAD Pathway Front Endocrinol (Lausanne) 2019 10:360-374
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD （通讯作者）, Jiang LS PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy International Journal of Biological Macromolecules 2019 136:1007-1017
余炜,朱超,茅伟伟,赵恩典,孟胜伟,蒋盛旦 （通讯作者） 神经肽P物质通过诱导RUNX2表达影响小鼠成骨细胞增殖能力 上海交通大学学报（医学版） 2017 37（1）：15-21
Yu W, Zhu C, Xu W, Jiang L, Jiang S （通讯作者） Neuropeptide Y1 Receptor Regulates Glucocorticoid-Induced Inhibition of Osteoblast Differentiation in Murine MC3T3-E1 Cells via ERK Signaling. Int J Mol Sci 2016 17(12): E2150
Zhu C, Zheng XF, Yang YH, Li B, Wang YR, Jiang SD （通讯作者）, Jiang LS LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway. Cell Signal 2016 28(8):989-1000
Li B, Su YJ, Zheng XF, Yang YH, Jiang SD （通讯作者）, Jiang LS Evidence for an Important Role of Smad-7 in Intervertebral Disc Degeneration. J Interferon Cytokine Res 2015 35(7):569-79
Chen JW, Ni BB, Zheng XF, Li B, Jiang SD （通讯作者）, Jiang LS. Hypoxia facilitates the survival of nucleus pulposus cells in serum deprivation by down-regulating excessive autophagy through restricting ROS generation Int J Biochem Cell Biol 2015 59:1-10
Chen JW, Ni BB, Li B, Yang YH, Jiang SD （通讯作者）, Jiang LS. The responses of autophagy and apoptosis to oxidative stress in nucleus pulposus cells: implications for disc degeneration. Cell Physiol Biochem 2014 34(4):1175-1189
Yang YH, Li B, Zheng XF, Chen JW, Chen K, Jiang SD （通讯作者）, Jiang LS Oxidative damage to osteoblasts can be alleviated by early autophagy through the endoplasmic reticulum stress pathway--implications for the treatment of osteoporosis Free Radic Biol Med 2014 77:10-20
Jiang SD, Chen JW, Yang YH, Chen XD, Jiang LS Intraobserver and interobserver reliability of measures of cervical sagittal rotation BMC Musculoskeletal Disorders 2014 15():332-336
Yang YH, Wang YR, Jiang SD （通讯作者）, Jiang LS Proximal femoral nail antirotation and third-generation Gamma nail: which is a better device for the treatment of intertrochanteric fractures? Singapore Med J 2013 54(8):446-450
Yang YH, Chen K, Li B, Chen JW, Zheng XF, Wang YR, Jiang SD （通讯作者）, Jiang LS Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway Apoptosis 2013 18(11):1363-1375
Jiang SD, Yang YH, Chen JW, Jiang LS Isolated osteoblasts from spinal cord-injured rats respond less to mechanical loading as compared with those from hindlimb-immobilized rats. J Spinal Cord Med 2013 36(3):224-226
Jiang SD, Chen JW, Jiang LS Which procedure is better for lumbar interbody fusion: anterior lumbar interbody fusion or transforaminal lumbar interbody fusion? Arch Orthop Trauma Surg 2012 132(9):1259-66
Jiang SD, Jiang LS, Dai LY. Anterior cervical discectomy and fusion versus anterior cervical corpectomy and fusion for multilevel cervical spondylosis: a systematic review. Arch Orthop Trauma Surg 2012 132(2):155-61
Jiang SD, Wu QZ, Lan SH, Dai LY Reliability of the measurement of thoracolumbar burst fracture kyphosis with Cobb angle, Gardner angle, and sagittal index. Arch Orthop Trauma Surg 2012 132(2):221-5
Yan J, Li B, Chen JW, Jiang SD （通讯作者）, Jiang LS. Spinal cord injury causes bone loss through peroxisome proliferator-activated receptor-γ and Wnt signalling. J Cell Mol Med 2012 16(12):2968-77
Jiang SD, Jiang LS, Dai LY Cervical spondylotic amyotrophy Eur Spine J 2011 20(3):351-7
Jiang SD, Jiang LS, Dai LY Degenerative cervical spondylolisthesis: a systematic review Int Orthop 2011 35(6):869-75
Jiang SD, Yan J, Jiang LS, Dai LY Down-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in osteoblasts from rats with chronic spinal cord injury Joint Bone Spine 2011 78(5):488-92
Jiang SD, Jiang LS, Dai LY Extreme lateral lumbar disc herniation in a 12-year child: case report and review of the literature Eur Spine J 2010 19(2):197-9
Jiang SD, Jiang LS, Zhao CQ, Dai LY No advantages of Gamma nail over sliding hip screw in the management of peritrochanteric hip fractures: a meta-analysis of randomized controlled trials Disabil Rehabil 2008 30(7):493-7
Jiang SD, Jiang LS, Dai LY Surgical treatment of calcaneal fractures with use of beta-tricalcium phosphate ceramic grafting Foot Ankle Int 2008 29(10):1015-9
Dai LY, Jiang SD （共同第一作者）, Wang XY, Jiang LS A review of the management of thoracolumbar burst fractures Surg Neurol 2007 67(3):221-31
Jiang SD, Jiang LS, Dai LY Changes in bone mass, bone structure, bone biomechanical properties, and bone metabolism after spinal cord injury: a 6-month longitudinal study in growing rats Calcif Tissue Int 2007 80(3):167-75
Jiang SD, Jiang LS, Dai LY Effects of spinal cord injury on osteoblastogenesis, osteoclastogenesis and gene expression profiling in osteoblasts in young rats Osteoporos Int 2007 18(3):339-49
Jiang SD, Jiang LS, Dai LY Horner Syndrome due to a solitary osteochondroma of C7: a case report and review of the literature Spine 2007 32(16):471-4
Jiang SD, Jiang LS, Dai LY Differences of bone mass and bone structure in osteopenic rat models caused by spinal cord injury and ovariectomy Osteoporos Int 2007 18(6):743-50
Jiang SD, Jiang LS, Dai LY Mechanisms of osteoporosis in spinal cord injury Clin Endocrinol 2006 65(5):555-65
Jiang SD, Jiang LS, Dai LY Spinal cord injury causes more damage to bone mass, bone structure, biomechanical properties and bone metabolism than sciatic neurectomy in young rats Osteoporos Int 2006 17(10):1552-61
Jiang SD, Jiang LS, Dai LY Osteoporosis after spinal cord injury Osteoporos Int 2006 17(2):180-92
蒋盛旦, 戴力扬 脊髓损伤后骨代谢 临床骨科杂志 2004 7(2):237-239
蒋盛旦,戴力扬 糖皮质激素诱导的骨质疏松发生机制 中国矫形外科杂志 2004 12(6):459-460