导师姓名： 耿红全 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属新华医院 三级学科/
专业领域： 泌尿外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： genghongquan@xinhuamed.com.cn（优先联系本邮箱）
邮编： 200082 邮箱地址： ghongquan@hotmail.com

研究方向 (点击浏览详细信息)
儿童先天性肾积水的自然病程及转归
儿童泌尿系结石的基因诊断及治疗

社会任职
上海市医学会小儿外科分会委员
中华医学会小儿外科分会泌尿学组委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
18XD** 胸腺素B4促进MSC源exosomes干预肾间质纤维化的机制研究 上海市优秀学术带头人计划 2018-05~2021-04 40万元 课题负责人
** 利用基因编辑技术构建大鼠PH1模型并开展基因治疗研究 国家自然科学基金委员会资助面上项目 2018-01~2021-12 83万元 课题负责人
0000 基于基因编辑技术构建大鼠PH1模型并开展基因治疗研究 上海市卫计委优秀学科带头人培养计划 2017-09~2019-12 45万元 课题负责人
** 功能蛋白修饰的膀胱无细胞基质作为膀胱替代材料的研究 国家自然基金委 2012-01~2015-12 60万元 课题负责人
** 长期缓释生长因子的膀胱胶原基质片作为膀胱替代材料的实验研究 国家自然基金委 2010-1~2010-12 8万元 主要责任人
长期缓释生长因子的膀胱胶原基质片作为膀胱替代材料的研究 上海市科委 2008-11~2011-10 10万元 主要责任人
05BZ50 复合VEGF基因的膀胱无细胞基质诱导膀胱再生的实验研究 上海市教委,发展基金 2005-09~2007-12 6万元

学术论文 作者论文标题期刊名出版年卷期页码
Chen H, Lin H, Xu M, Xu G, Fang X, He L, Chen Z, Wu Z, Geng H. （通讯作者） Quantitative Urinary Proteome Reveals Potential Biomarkers for Ureteropelvic Junction Obstruction. Proteomics. Clinical Applications 2019 2019 Jul;13(4):e**.
Fang X, He L, Xu G, Lin H, Xu M, Geng H. （通讯作者） Nine novel HOGA1 gene mutations identified in primary hyperoxaluria type 3 and distinct clinical and biochemical characteristics in Chinese children. Pediatr Nephrology 2019 2019 May 23. doi: 10.1007/s00467-019-04279-7. [Epub ahead of print]
He L, Xu G, Fang X, Lin H, Xu M, Yu Y, Geng H. （通讯作者） Identification of 8 novel gene variants in primary hyperoxaluria in 21 Chinese children with urinary stones. World Journal of Urology 2019 2019 Aug;37(8):1713-1721.
Jiang D,Chen Z,Lin H,Xu M,Geng H. （通讯作者） Predictive Factors of Contralateral Operation after Initial Pyeloplasty in Children with Antenatally Detected Bilateral Hydronephrosis Due to Ureteropelvic Junction Obstruction. UROLOGIA INTERNATIONALIS 2018 100(3):322-326
Zheng R, Fang X, He L, Shao Y, Guo N, Wang L, Liu M, Li D, Geng H. （通讯作者） Generation of a Primary Hyperoxaluria Type 1 Disease Model Via CRISPR/Cas9 System in Rats. Current Molecular Medicine 2018 2018;18(7):436-447.
Xu G, He L, Fang X, Jiang D, Jin L, Lin H, Xu M, Wu Y, Geng H （通讯作者） Management of Renal Artery Occlusion Related to Multiple Trauma in Children: Two Case Reports. urology 2017 101:154-157
Xu G, Xu M, Ma J, Chen Z, Jiang D, Hong Z, Lin H, Fang X, Wang L, He L, Geng H. （通讯作者） An initial differential renal function between 35% and 40% has greater probability of leading to normal after pyeloplasty in patients with unilateral pelvic-ureteric junction obstruction. Int Urol Nephrol 2017 Aug 9. doi: 10.1007/s11255-017-1665-0
Jiang D, Tang B, Xu M, Lin H, Jin L, He L, Xu G, Fang X, Geng H. （通讯作者） Functional and Morphological Outcomes of Pyeloplasty at Different Ages in Prenatally Diagnosed Society of Fetal Urology Grades 3-4 Ureteropelvic Junction Obstruction: Is It Safe to Wait? urology 2017 101:45-49.
Jiang D, Geng H. （通讯作者） Primary Hyperoxaluria. N Engl J Med. 2017 13;376(15)
Lin H, Xu M, Jiang D, Xu G, Fang X, He L, Geng H. （通讯作者） Iatrogenic Fibroepithelial Polyps in Children With Hydronephrosis. Urology 2017 104:172-174
Jiang D, Chen Z, He L, Lin H, Jin L, Xu M, Xu G, Fang X, Geng H. （通讯作者） Repair of Urethrovaginal Fistula Secondary to Pelvic Fracture With a Labia Minora Skin Flap in Young Girls. Urology 2017 103:227-229
Lin H, Xu M, Jiang D, Xu G, Fang X, Jia J, Wu Y, He L, Geng H. （通讯作者） Non-cystoscopic Removal of Retained Ureteral Stents With Mild Sedation in Children Urology 2016 94:255-8
Jiang X, Lin H, Jiang D, Xu G, Fang X, He L, Xu M, Tang B, Wang Z, Cui D, Chen F, Geng H （通讯作者） Co-delivery of VEGF and bFGF via a PLGA nanoparticle-modified BAM for effective contracture inhibition of regenerated bladder tissue in rabbits. Sci Rep 2016 8;6:20784-96.
Jiang X, Xiong Q, Xu G, Lin H, Fang X, Cui D, Xu M, Chen F, Geng H （通讯作者） VEGF-Loaded Nanoparticle-Modified BAMAs Enhance Angiogenesis and Inhibit Graft Shrinkage in Tissue-Engineered Bladder. Ann Biomed Eng 2015 43(10):2577-86
Xiong Q,Lin H,Hua X,Liu L,Sun P,Zhao Z,Shen X,Cui D,Xu M, Chen F,Geng H. （通讯作者） A nanomedicine approach to effectively inhibit contracture during bladder acellular matrix allograft-induced bladder regeneration by sustained delivery of vascular endothelial growth factor. Tissue Eng Part A 2015 21(12):45-52
Ma Q,Tang Y,Lin H,Xu M,Xu G,Fang X,Chen J,Song Z,Li Z,Shi Y,Geng H. （通讯作者） DGKK Variants and hypospadias in Han Chinese: association and meta-analysis. BJU International 2014 10(2):40-45
Jianye Jia, Xiaowei Shen, Liya Wang, Tiejun Zhang, Maosheng Xu, Xiaoliang Fang, Guofeng Xu, Chen Qian, Yeming Wu, Hongquan Geng （通讯作者） Extracorporeal Shock Wave Lithotripsy is Effective in Treating Single Melamine Induced Urolithiasis in Infants and Young Children The Journal of Urology 2013 189(4):1498-502
Geng H, Xu M, Fang X, Shen X, Lin H. Pseudoduplication of the external genitalia Eur J Pediatr 2013 172(12):1693-5
Shen X, Xv M, Liu G, Xu G, Wu Y, Lin H, Geng H. （通讯作者） Ureteral replacement with appendix in a pediatric group: a report of two cases and review of the literature. Eur J Pediatr Surg. 2012 22(4):329-31
Sun P, Song H, Cui D, Qi J, Xu M, Geng H. （通讯作者） Preparation and optimization of matrix metalloproteinase-1-loaded poly(lactide-co-glycolide-co-caprolactone) nanoparticles with rotatable central composite design and response surface methodology. Nanoscale Res Lett. 2012 7(1):359-367
钱晨、林厚维、孙平、徐国峰、徐卯升、杨涛、耿红全# 尿道下裂的MAMLD1基因研究 临床小儿外科杂志 2012 11（2）:106-108
Geng H （共同第一作者）, Song H, Qi J, Cui D. Sustained release of VEGF from PLGA nanoparticles embedded thermo-sensitive hydrogel in full-thickness porcine bladder acellular matrix. Nanoscale Res Lett. 2011 7;6(1):312-316.
Geng H （共同第一作者）, Xu G, Ran Y, López JA, Peng Y Platelet glycoprotein Ib beta/IX mediates glycoprotein Ib alpha localization to membrane lipid domain critical for von Willebrand factor interaction at high shear. J Biol Chem 2011 17;286(24):21315-23.