摘要/Abstract
脱氢偶联反应是最有效、最直接的构建C—C键或C—杂键的一种方法. 但是目前大多数脱氢偶联反应需要使用化学计量的有毒氧化剂, 如PhI(OAc)2、苯醌、Cu(II)盐、有机过氧酸或Ag(I)盐等. 氧气廉价易得, 作为脱氢偶联反应中的唯一氧化剂, 副产物只有水, 不会产生其他有毒副产物, 是绿色环境友好的方法. 根据催化剂的分类, 综述了氧气作为唯一氧化剂的交叉脱氢偶联反应研究进展.
关键词: 交叉脱氢偶联, 氧气, 唯一氧化剂
Cross-dehydrogenative-coupling (CDC) reactions have emerged as one of the most efficient and straightforward methods for the formation of C—C bonds or C-heteroatom bonds. However, most CDC reactions require hazardous and stoichiometric oxidants, such as PhI(OAc)2, benzoquinone, copper(II) salts, organic peroxide acid and silver(I) salts. A green and environmentary benign approach is using molecular oxygen (O2) as oxidant in the reactions, which usually form water as by-product. According to the classification of catalysts, the research progress of cross dehydrogenation coupling reaction with oxygen as the only oxidant is reviewed.
Key words: cross-dehydrogenative-coupling, molecular oxygen, oxidant
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