摘要/Abstract
以1,3-二酮、苯甲醛和醋酸铵为原料,成功地开发了一种简便、高效、无溶剂和催化剂的三组分一锅合成法,高收率地得到了2,4,6-三芳基嘧啶化合物.此方法提供了一条"绿色"合成嘧啶骨架新策略.
关键词: 无催化剂, 无溶剂, 一锅法, 三组分反应, 2,4,6-三芳基嘧啶
2,4,6-Triarylpyrimidines were synthesized via a simple, efficient, one-pot, three-component reaction from 1,3-dikeones, benzaldehydes and ammonium acetate under solvent-free and catalyst-free conditions in good to excellent yields. This "green" methodology provides an eco-friendly protocol for the construction of the pyrimidine framework.
Key words: catalyst-free, solvent-free, one-pot, three-component reaction, 2,4,6-triarylpyrimidine
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