摘要/Abstract
以二叔丁基过氧化物为氧化剂，1，4-二氮杂二环[2.2.2]辛烷（DABCO）为助催化剂，通过乙酰丙酮镍催化的芳香烃偶联反应，建立了一种制备联苄化合物的方法.该方法对不同芳烃底物具有耐受性，其中，异丙苯最容易发生反应，联苄的收率达到73%.优化条件下芳香烃与环烷烃也可发生交叉偶联作用，但伴随两种底物的自偶联反应.该方法能有效抑制醇、醛和酸的产生.
关键词: 芳香烃, 偶联反应, 二叔丁基过氧化物, 乙酰丙酮镍, 联苄
A protocol for the synthesis of bibenzyls via nickel acetylacetonate-catalyzed coupling of arenes was devloped using di-tert-butylperoxide as the oxidant with the asistance of 1,4-diazabicyclo[2.2.2]octane (DABCO). The process tolerated to different substrates, among of which, isopropylbenzene provided the most satisfactory yield of bibenzyls in 73% yield. The cross-coupling of arenes with cycloalkanes was also realized under the optimal reaction conditions but accompanied with the self-coupling of substrates. The method could effectively restrain the formation of alcohol, aldehyde, acid.
Key words: arene, coupling, di-tert-butylperoxide, nickel(II) acetylacetonate, bibenzyl
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