摘要/Abstract

在常见氧化剂叔丁基过氧化氢（TBHP）的存在下，成功开发了一种选择性将硫醚氧化成亚砜，将二硫醚氧化成单砜的新方法，得到一系列亚砜和单砜类化合物，收率为67%~98%.该方法具有不使用任何催化剂和添加剂、底物适用性广、反应效率高、选择性好等优点.此外，通过控制实验，提出了一种合理的自由基反应机理.
关键词: 硫醚/二硫醚, 亚砜/单砜, 叔丁基过氧化氢, 氧化反应, 无催化剂添加剂
A novel and simple method for the selectively oxidation of sulfides to sulfoxides and oxidation of disulfides to thiosulfonates in the presence of t-butyl hydroperoxide (TBHP) has been established. The oxidation system has the advantages of avoiding the use of any catalyst and additive, possessing a broad substrate scope and high efficiency. Desired sulfoxides and thiosulfonates products were obtained in moderate to good yields. Furthermore, a plausible mechanism of the reaction is proposed. The results of control experiments revealed that a radical pathway was involved in this oxidation.
Key words: sulfides/disulfides, sulfoxides/thiosulfonates, t-butylhydroperoxide, oxidation, catalyst/additive free


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