摘要/Abstract

四个含NN型双齿配体的半夹心（h⁶-p-cymene）Ru（II）化合物被成功制备.这四个化合物分别为（h⁶-p-cymene）-Ru（C₅H₄N-C₅H₃N-OH）（1），（h⁶-p-cymene）Ru（C₅H₄N-CH₂-C₅H₄N）（2），（h⁶-p-cymene）Ru（C₅H₄N-CH₂-C₅H₃N-OH）（3）和（h⁶-p-cymene）Ru（C₅H₄N-CH₂-C₅H₃N-OCH₃）（4）.这些化合物通过核磁氢谱、碳谱和元素分析等手段表征，化合物2的结构被X射线单晶衍射证实.将这些化合物应用于催化氨醇与酮的环化反应，其中3的催化效率最高.在0.5 mol%化合物3的存在下，制备了一系列喹啉和吡啶衍生物.
关键词: 半夹心, 钌, 无受体脱氢环化, 双齿配体, 2-羟基吡啶
Four (h⁶-p-cymene)Ru(II) complexes with bidentate NN ligands, (h⁶-p-cymene)Ru(C₅H₄N-C₅H₃N-OH) (1), (h⁶-p-cymene)Ru(C₅H₄N-CH₂-C₅H₄N) (2), (h⁶-p-cymene)Ru(C₅H₄N-CH₂-C₅H₃N-OH) (3) and (h⁶-p-cymene)Ru(C₅H₄N-CH₂-C₅H₃N-OCH₃) (4) were prepared. These complexes were all characterized by¹H NMR, ¹³C NMR and elemental analysis, and complex 2 was further determined by single crystal crystallography. Complexes 1~4 were treated as catalysts for cyclizations of amino alcohols with ketones, and complex 3 exhibited the highest activity. The cyclization reactions proceeded in toluene with 0.5 mol% catalyst loading, and a series of quinolines and pyrroles were synthesized.
Key words: half-sandwich, ruthenium, acceptorless dehydrogenative cyclization, bidentate ligand, 2-hydroxypyridine


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