摘要/Abstract
以芳香醛、脲和醇为原料,过量的醇为溶剂,D-脯氨酸为催化剂,开发了一种简单的多组分一锅法合成N,O-缩醛化合物的方法.在室温下反应30 h后,以良好的收率合成了一系列N,O-缩醛化合物.
关键词: D-脯氨酸, N,O-缩醛化合物, 一锅法合成, 室温
In this paper, a convenient method for multi-component one-pot synthesis of N,O-acetal compounds was developed, using aromatic aldehyde, urea and alcohol as materials, alcohol also as solvent and D-proline as catalyst. A series of N,O-acetal compounds were synthesized in good yields after reacting for 30 h at room temperature.
Key words: D-proline, N,O-acetal compounds, one-pot synthesis, room temperature
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