摘要/Abstract

1，1-二氯烯烃结构存在于许多天然产物中，同时也是一类重要的合成中间体，广泛应用于炔烃、卤代炔烃以及芳烃化合物的合成.报道了一个新的1，1-二氯烯烃化试剂：二氯甲基（2-吡啶基）砜.以叔丁醇钾作为碱，二氯甲基（2-吡啶基）砜与芳香醛顺利反应，以良好的产率制备得到了1，1-二氯烯烃化合物.该方法实验操作简便、试剂易得且纯化方便.
关键词: 二氯甲基砜, 1,1-二氯烯烃, 芳香醛
The 1,1-dichloroalkene structural unit is found in many natural products. 1,1-Dichloroalkenes are important intermediates, which have been widely used in the synthesis of alkynes, halogenated acetylenes and aromatic compounds. In this paper, a new dichloroolefinating reagent, dichloromethyl 2-pyridyl sulfone, was reported. 1,1-Dichloroalkenes can be conveniently obtained from the reaction of dichloromethyl 2-pyridyl sulfone with aromatic aldehydes using t-BuOK as base. This method has the advantage of operational simplicity, usage of easily available reagents and easy purification, which may find applications in organic synthesis.
Key words: dichloromethyl sulfone, 1,1-dichloroalkenes, aromatic aldehydes


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