摘要/Abstract

探索了在路易斯酸催化下，三氟甲基酰腙与三甲基氰硅烷的1，2-加成反应，得到了一系列含有三氟甲基的氰基酰肼类化合物.该方法具有反应条件温和、操作简单、产率高等特点，为合成结构多样的含三氟甲基的酰肼类化合物提供了一种有效的方法.
关键词: 三氟甲基酰腙, 三甲基氰硅烷, 酰肼, 氰基化反应
The Lewis acid catalyzed 1,2-addition reaction of trifluoromethylated acylhydrazones with trimethylsilyl cyanide was investigated, and a series of cyanohydrazide compounds containing trifluoromethyl group were afforded in high yield. The method could be easily operated in mild reaction conditions, which provides an efficient method for the synthesis of trifluoromethylated hydrazides with structural diversity.
Key words: trifluoromethylated acylhydrazones, trimethylsilyl cyanide, acylhydrazides, hydrocyanation


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