摘要/Abstract

报道了室温条件下烯胺酮和磺酰叠氮通过碳-碳双键断裂合成N-磺酰基醚类化合物的方法.反应在1，8-二氮杂双环[5.4.0]十一碳-7-烯（DBU）存在下进行，无需使用任何金属和氧化剂，具有良好的底物适用性.烯胺酮上的¹⁵N同位素标记实验证实，磺酰叠氮仅作为产物中的磺酰胺片段供体，同时，该实验也有力地支持反应机理涉及关键的1，2，3-三唑啉中间体的原位形成以及环分解.
关键词: 烯胺酮, 碳-碳双键断裂, 无金属, 无氧化剂, 脒
The C=C double bond cleavage of NH₂-functionalized enaminones has been realized at room temperature to provide various N-sulfonyl amidines by reacting with sulfonyl azides. The reactions take place with good substrate tolerance in the presence of 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) without any metal or oxidant reagent. The ¹⁵N-labelling experiment on enaminone indicates that the sulfonyl azide component donates solely the sulfonamide fragment, and the reaction mechanism involving a key decomposition of the in situ generated 1,2,3-triazoline intermediate is convictively supported.
Key words: Enaminone, C=C bond cleavage, Metal-free, Oxidant-free, Amidines


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