摘要/Abstract

设计、合成了一种基于新型萘环稠合硼氟二吡咯化合物（BODIPY）5的氟离子比率计量型和荧光猝灭型分子探针.通过紫外-可见光谱实验发现，该探针在氟离子存在时光谱红移100 nm，进入近红外区域，可用于肉眼比色检测.荧光光谱分析表明，氟离子可促使荧光猝灭.细胞成像研究表明探针分子5可在活体细胞中专一性地识别氟离子.
关键词: 硼氟二吡咯化合物(BODIPY), 近红外, 氟离子, 细胞成像
A colorimetric and fluorescent turn-off chemosensor for fluoride based on novel naphthalene-fused boron dipyrromethene (BODIPY) 5 was designed and synthesized. In various anions, only upon addition of fluoride, the UV-Vis absorption peak of probe 5 red-shifted 100 nm, reaching the near infrared (NIR) region. Thus, it can be used as naked-eye detector for fluoride ion. In the fluorescence test, upon addition of fluoride, the fluorescence of probe 5 quenched significantly. Confocal fluorescence microscopy experiments demonstrate that 5 can be used for monitoring fluoride in living cells.
Key words: boron dipyrromethene (BODIPY), near infrared (NIR), fluoride, fluorescent sensor


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