摘要/Abstract

以二（2-吡啶甲基）胺（DPA）和三聚茚为原料，设计合成了一种"turn-off"型荧光探针化合物6，表征了其结构，研究了它对不同金属离子的识别作用.结果表明，化合物6对Cu²⁺和Ni²⁺具有较高的灵敏性和选择性，在N，N-二甲基甲酰胺（DMF）/H₂O（V/V=8/2，pH=7.0）溶液中对Cu²⁺、Ni²⁺显示出荧光淬灭效应，且对Cu²⁺检测几乎不受其他金属离子的干扰；高分辨质谱证明化合物6与Cu²⁺、Ni²⁺结合计量比为1：1；化合物6对Cu²⁺的检测极限可低至28 nmol/L，对Ni²⁺的检测极限可低至41 nmol/L，检测极限均低于世界卫生组织（WHO）规定的饮用水中两种离子最大含量，有潜在的应用价值.
关键词: 三聚茚, 二(2-吡啶甲基)胺, 荧光探针, Cu²⁺, Ni²⁺
A new turn-off probe 6 was synthesized from bis(pyridin-2-ylmethyl)amine and truxene derivatives, and its structure was confirmed by ¹H NMR and HRMS. The recognition behaviors of 6 to various metal ions were investigated and the results show that 6 exhibited good selectivity and high sensitivity to Cu²⁺ and Ni²⁺ with good anti-interference. The probe 6 presented apparent fluorescence quenching in DMF/H₂O (V/V=8/2, pH=7.0) solution toward Cu²⁺ and Ni²⁺. HRMS analysis showed a 1:1 binding stoichiometry between 6 and Cu²⁺ or Ni²⁺. The detection limit for Cu²⁺ and Ni²⁺ was calculated to be 28 and 41 nmol/L, respectively. The detection limit of 6 for Cu²⁺ and Ni²⁺ was far lower than the maximum allowable level of World Health Organization (WHO) limit for drinking water.
Key words: truxene, bis(pyridin-2-ylmethyl)-amine (DPA), fluorescent sensor, Cu²⁺, Ni²⁺


PDF全文下载地址:

点我下载PDF