摘要/Abstract

制备了一种聚乙二醇接枝4-二甲氨基吡啶功能化离子液体（[DMAP-PEG₁₀₀₀-DIL][BF₄]），采用¹H NMR、¹³C NMR、FT-IR、ESI-MS对其进行结构表征.在[DMAP-PEG₁₀₀₀-DIL][BF₄]催化下，具有不同取代基的芳香醛均可与丙二腈（或氰乙酸乙酯）、邻苯二甲酰肼在水介质中顺利反应，以85%~96%的产率合成了一系列吡唑并[1，2-b]酞嗪-5，10-二酮化合物.该方法具有反应条件温和，离子液体稳定性高且可回收利用，对环境友好等优点.
关键词: 聚乙二醇, 离子液体, 4-二甲氨基吡啶, 吡唑并[1,2-b]酞嗪-5,10-二酮, 水介质
A novel poly(ethylene glycol) grafted 4-dimethylaminopyridine functionalized ionic liquid ([DMAP-PEG₁₀₀₀-DIL] [BF₄]) was prepared and characterized by ¹H NMR, ¹³C NMR, FT-IR and ESI-MS. In the presence of[DMAP-PEG₁₀₀₀-DIL] [BF₄], various substituted aromatic aldehyde could react with malononitrile (or ethyl cyanoacetate) and phthalhydrazide in water to obtain a series of pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with 85%~96% yields. The mild reaction conditions, high stable and recyclable ionic liquids, environmental friendliness are advantages of this methodology.
Key words: poly(ethylene glycol), ionic liquid, 4-dimethylaminopyridine, pyrazolo[1,2-b]phthalazine-5,10-dione, aqueous media


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