摘要/Abstract
研究了水相三乙胺催化3，5-二烷基-4-硝基异噁唑与三氟甲基酮的亲核加成反应，以66%～99%的产率合成了一系列三氟甲基叔醇衍生物.通过脱水或氧化反应可有效的将目标产物转化为烯烃或羧酸类化合物.
关键词: 水相, 亲核加成, 3,5-二烷基-4-硝基异噁唑, 三氟甲基酮
The triethylamine catalyzed nucleophilic addition of 3, 5-dialkyl-4-nitroisoxazoles to trifluoromethyl ketones on water has been realized affording trifluoromethyl tertiary alcohol derivatives in 66%～99% yields. The products were easily transformed to the resulting alkenes by dehydration or acids by oxidation.
Key words: on water, nucleophilic addition, 3, 5-dialkyl-4-nitroisoxazoles, trifluoromethyl ketones References
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