xm:周虎
xb:男
zc:研究员
xl:博士
dh:-3108
cz:
dzyj:zhouhu@simm.ac.cn
grzy:
zjlb:研究员
zw:课题组长
txdz:上海市浦东新区张江高科技园区祖冲之路555号3108室
grjj:周虎，博士，中国科学院上海药物研究所研究员/博士生导师/课题组长。研究方向为基于质谱的药物蛋白质组学研究：1）有机小分子和生物大分子相互作用的质谱方法学研究；2）转化蛋白质组学研究；3）药物蛋白质组学研究，以寻找药物小分子的作用靶点及其作用机制。2001年于南开大学获生物学学士学位。2007年于中科院上海生物化学与细胞生物学研究所获生物化学与分子生物学博士学位。2008年至2012年在渥太华大学系统生物学研究所进行博士后研究，期间担任质谱实验室主管。2012年3月担任中科院上海药物研究所研究员和课题组长。已在Cell、Theranostics、Ebiomedicine、Anal Chem等SCI期刊上发表论文100余篇（其中近五年发表60余篇），总影响因子>700，他引2068次，h指数33；第一作者或共同第一作者的论文11篇，通信或共同通信作者论文26篇。

yjfx:基于质谱的药物蛋白质组学研究
dblz: (1) Gao, Qiang#; Zhu, Hongwen#; Dong, Liangqing#; Shi, Weiwei#; Chen, Ran#; Song, Zhijian; Huang, Chen; Li, Junqiang; Dong, Xiaowei; Zhou, Yanting; Liu, Qian; Ma, Lijie; Wang, Xiaoying; Zhou, Jian; Liu, Yansheng; Boja, Emily; Robles, Ana I; Ma, Weiping; Wang, Pei; Li, Yize; Ding, Li; Wen, Bo; Zhang, Bing; Rodriguez, Henry; Gao, Daming*; Zhou, Hu*; Fan, Jia*; Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell, 2019, 179(2): 561-577.e22.

(2) Xiao, Ruoxuan#; Ding, Chunyong#; Zhu, Hongwen; Liu, Xia; Gao, Jing; Liu, Qian; Lu, Dayun; Zhang, Naixia*; Zhang, Ao*; Zhou, Hu*; Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer. Cancer Letters, 2020, 475: 22-33.

(3) Wang, Kuifeng#; Fang, Shanhua#; Liu, Qian#; Gao, Jing; Wang, Xiaoning; Zhu, Hongwen; Zhu, Zhenyun; Ji, Feihong; Wu, Jiasheng; Ma, Yueming; Hu, Lihong; Shen, Xu; Gao, Daming; Zhu, Jiansheng*; Liu, Ping*; Zhou, Hu*; TGF-beta1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM. EBioMedicine, 2019, 42: 458-469.

(4) Chen, Xiangling#; Yu, Chengli#; Gao, Jing#; Zhu, Hongwen; Cui, Binghai; Zhang, Tao; Zhou, Yanting; Liu, Qian; He, Han; Xiao, Ruoxuan; Huang, Ruimin; Xie, Hua; Gao, Daming; Zhou, Hu*; A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer. Theranostics, 2018, 8(9): 2348-2360.

(5) Xu, Jingjing#; Gao, Jing#; Yu, Chengli; He, Han; Yang, Yiming; Figeys, Daniel*; Zhou, Hu*; Development of Online pH Gradient-Eluted Strong Cation Exchange Nanoelectrospray-Tandem Mass Spectrometry for Proteomic Analysis Facilitating Basic and Histidine-Containing Peptides Identification. Analytical Chemistry, 2016, 88(1): 583-591.

(6) Chen, Xiangling#; Lu, Dayun#; Gao, Jing; Zhu, Hongwen; Zhou, Yanting; Gao, Daming; Zhou, Hu*; Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics. Journal of Proteome Research, 2019, 18(6): 2654-2665.

(7) Song, Hai#; Fang, Shanhua#; Gao, Jing; Wang, Jiaxong; Cao, Zhenzhen; Guo, Zeyun; Huang, Qiongping; Qu, Yongqang; Zhou, Hu*; Yu, Jianyun*; Quantitative Proteomic Study Reveals Up-Regulation of cAMP Signaling Pathway-Related Proteins in Mild Traumatic Brain Injury. Journal of Proteome Research, 2018, 17(2): 858-869.

(8) Gao, Jing#; Zhong, Shaoyun#; Zhou, Yanting; He, Han; Peng, Shuying; Zhu, Zhenyun; Liu, Xing; Zheng, Jing; Xu, Bin; Zhou, Hu*; Comparative Evaluation of Small Molecular Additives and Their Effects on Peptide/Protein Identification. Analytical Chemistry, 2017, 89(11): 5784-5792.

jyjl:2001.9-2007.6中国科学院上海生命科学研究院生物化学与细胞生物学研究所，生物化学与分子生物学博士学位