xm:廖苍松
xb:男
zc:研究员
xl:博士
dh:
cz:
dzyj:csliao@simm.ac.cn
grzy:
zjlb:研究员
zw:课题组长
txdz:上海市浦东新区半夏路100弄19号楼302
grjj: 廖苍松，2013年毕业于中科院上海药物研究所并取得博士学位，随后留所担任助理研究员。2014年11月加入瑞士巴塞尔大学化学系进行博士后研究。2020年1月回到上海药物所，担任课题组长。课题组主要从事生物催化级联反应，新颖活性天然产物发现研究等。前期相关工作发表于Nature Catalysis, Angew. Chem. Int. Ed.等国际学术期刊并申请欧洲专利一项。
yjfx:生物催化，酶级联反应不对称合成与新颖活性天然产物发现
dblz:1. Liao C.; Seebeck F.P. *. Asymmetric β‐Methylation of L‐ and D‐α‐Amino Acids by a Self‐Contained Enzyme Cascade. Angew. Chem. Int. Ed., 2020, 59, 7184-7187.2.Liao C.; Seebeck F.P. *. S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reactions. Nature Catalysis, 2019, 2, 696-701. Highlighted by Nature Catalysis News and Views (Nature Catalysis. 2019, 2, 644-645).3. Liao C.; Seebeck F.P. *. In vitro Reconstitution of Bacterial DMSP Biosynthesis. Angew. Chem. Int. Ed., 2019, 58, 3553-3556.4. Goncharenko, K.V.; Flückiger S.; Liao C.; Lim, D.; Stampfli A.R.; Seebeck, F. P*. Selenocysteine as a substrate, an inhibitor and a mechanistic probe for bacterial and fungal iron‐dependent sulfoxide synthases. Chemistry-A European Journal, 2020, 26, 1328-1334.5. Gamage A.M.; Liao C.; Cheah I.K.; Chen Y.; Lim D.R.X.; Ku J.W.K.; Chee R.S.L.; Gengenbacher M.; Seebeck F.P.; Halliwell B.; Gan Y.H*. The Proteobacterial Species Burkholderia Pseudomallei Produces Ergothioneine, which Enhances Virulence in Mammalian Infection. FASFEB J. 2018, 6395-6409.6. Liao C.; Seebeck F.P. *. Convergent Evolution of Ergothioneine Biosynthesis in Cyanobacteria. Chembiochem, 2017, 18, 2115-2118.7. Ruan J.; Liao C.; Ye Y.; Lin G*. Lack of Metabolic Activation of Predominant Formation of an Excreted Metabolite of Nontoxic Platynecine-Type Pyrrolizidine Alkaloids. Chem. Res. Toxcicol. 2014, 27, 7-16.8. Liao C.; Tang C-P.; Yao S.; Ye Y.*. Humulane-type sesquiterpenoids from Pilea cavaleriei subsp. crenata. Org. Biomol. Chem., 2013, 11, 4840-4846.
jyjl: 中国药科大学 制药工程专业 工学学士
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