杨士红1,
尤国祥2,
侯俊2,,
1. 河海大学农业科学与工程学院, 南京 210098;
2. 河海大学环境学院, 浅水湖泊综合治理与资源开发教育部重点实验室, 南京 210098
作者简介: 许伊(1990-),女,博士,研究方向为农业水土环境,E-mail:xuyi_0623@126.com.
通讯作者: 侯俊,hjy_hj@hhu.edu.cn
基金项目: 国家自然科学基金资助项目（52039003）；中央高校基本科研业务费专项资金资助项目（B210202114）；国家自然科学基金青年基金资助项目（52009031）；中国博士后科学基金面上项目（2020M671326，2020M681478）中图分类号: X171.5
Review of the Potential Ecological Risks and Toxicity Mechanisms of Nanoceria
Xu Yi1,2,Yang Shihong1,
You Guoxiang2,
Hou Jun2,,
1. College of Agricultural Science and Engineering, Hohai University, Nanjing 210098, China;
2. Key Laboratory of Integrated Regulation and Resources Development on Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China
Corresponding author: Hou Jun,hjy_hj@hhu.edu.cn
CLC number: X171.5
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摘要:作为重要的纳米稀土化合物，纳米二氧化铈（CeO2）被广泛应用于工、农、医学等领域，随之而来的是大量的纳米CeO2在其生产使用和处理处置等过程中被释放进入到环境中，进而导致其生物安全性受到越来越多的关注。本文从纳米CeO2对细胞、组织器官、植物、水生生物和土壤生物产生的毒性效应入手，系统综述了纳米CeO2的潜在环境生态风险；进一步从物理损伤和化学抑制2个方面剖析了纳米CeO2的生物毒性作用机制；最后基于已有的关于纳米CeO2生态风险的研究中存在的不足对未来发展方向进行了展望。本文旨在为纳米CeO2的生态安全评价提供理论基础和科学依据。
关键词: 纳米二氧化铈/
植物/
微生物/
细胞毒性/
氧化损伤/
生态风险
Abstract:As one of the most important nano-rare earth compounds, nanoceria (nano-CeO2) has been widely applied in industrial, agricultural and medical areas. Subsequently, large amounts of nano-CeO2 are inevitably released into the environment during their production, utilization and disposal processes. Thereby, the biological safety of released nano-CeO2 has attracted more and more attention. In this paper, the toxicity effects of nano-CeO2 on cells, tissue and organs, plants, aquatic organisms and soil organisms are systemically reviewed to illustrate the potential ecological environmental risks of nano-CeO2. Furthermore, the biotoxicity mechanisms of nano-CeO2 are explored from the aspects of physical damage and chemical inhibition. At last, the further research directions are proposed based on the shortages existing in the current studies about the ecological risks of nano-CeO2. The aim of this review is to provide theoretical and scientific basis for the evaluation of the ecological safety of nano-CeO2.
Key words:nano-ceria/
plant/
microbes/
cytotoxicity/
oxidative damage/
ecological risks.
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