王安1,,,
杨秀鸿2,,
1. 中南大学湘雅公共卫生学院卫生毒理学系, 长沙 410078;
2. 湖南省职业病防治院毒理实验室, 长沙 410007
作者简介: 杨嘉辉(1995-),男,硕士研究生,研究方向为毒理学安全性评价,E-mail:otztoxin@163.com.
通讯作者: 王安,csuwang@csu.edu.cn ; 杨秀鸿,yxh502@sina.com
中图分类号: X171.5
Reproductive Toxicity and Genotoxicity of Herbicides to Non-target Organisms and Human Beings
Yang Jiahui1,Wang An1,,,
Yang Xiuhong2,,
1. Department of Toxicology, XiangYa School of Public Health, Central South University, Changsha 410078, China;
2. Toxicology Laboratory, Hunan Prevention and Treatment Institute for Occupational Diseases, Changsha 410007, China
Corresponding authors: Wang An,csuwang@csu.edu.cn ; Yang Xiuhong,yxh502@sina.com
CLC number: X171.5
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摘要:除草剂的应用已逐渐成为农业生产中不可或缺的一环。除草剂潜在的毒性作用对生态系统及其中生存的动物和人类存在着威胁。因此，研究除草剂的生殖和遗传毒性并选用安全的品类对于生态系统的保护是十分重要的。本文综述了多种除草剂对几种非靶标生物的生殖毒性和遗传毒性，为新型除草剂的生殖和遗传毒性评价及实验动物的选择提供参考，并为除草剂的生态毒理研究提供思路。
关键词: 除草剂/
非靶标生物/
生殖毒性/
遗传毒性
Abstract:The application of herbicides has gradually become an indispensable part of agricultural production. The potential toxicity of herbicides is a threat to not only the ecosystems but also to the organisms and human beings living in them. Therefore, the researches on the reproductive toxicity and genotoxicity of herbicides and the correct selection of safe herbicides are essential for protecting the ecosystem. In this review, the reproductive toxicity and genotoxicity of several herbicides to non-target organisms were introduced, which provided reference for the selection of test method and experimental animal for reproductive toxicity and genotoxicity evaluation of new herbicides, as well as the ideas for the ecotoxicological study of herbicides on environmental organisms and human beings.
Key words:herbicide/
non-target organism/
reproductive toxicity/
genotoxicity.
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