Youxin Li——Associate Professor
Nationality:
CHINA

Phone:


Email:
lyx@tju.edu.cn

Office:
Room C412-8, Building 24, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
K-1567-2015

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Education Experience
2007-2010 Ph. D. Tianjin University, CN

Professional Experience
2010- Associate Professor Tianjin University.
2017- Visting scholar Purdue University

Research Area
Li’s research addresses development and application of electrophoresis techniques,heterogeneous catalysis and applications, chiral separation and applications, sample preparation and application, and high throughput drug screening based on hollow fiber member system development.




Honors and Awards
李优鑫，天津大学药学院第三届青年教师讲课大赛，一等奖，2012.4
包建民，马志爽，宋文青，孙莹，李优鑫*，“新型复合固相萃取柱-紫外法快速检测牛奶中三聚氰胺”一等论文并编入“2012中国食品与农产品质量安全检测技术应用国际论坛暨展览会”论文集，北京，2012.5.22.
李优鑫，天津大学“第九届青年教师讲课大赛”三等奖，2012.6
Youxin Li, Third annual SLAS Conference and Exhibition (SLAS2014), San Diego, CA, USA, 2014, January 18-22th, Tony B. Academic Travel Award.
李优鑫，第十届全国生物医药色谱及相关学术交流会，2014.4.19-22，山东?威海，优秀报告奖
李优鑫，天津市第十三届青年教师教学基本功竞赛校内选拔赛，理科组，三等奖，2016.6

Patents
6. 张勇，包建民，李优鑫，肖红亭，付霞，毛细管电泳速差模式测定化合物对映体过剩值的装置，发明专利，专利号：5.7，授权日：2016.9.7
5. 李优鑫，包建民，宝贵荣，一种测定血浆中游离化合物浓度、logD和化合物蛋白结合率的方法，发明专利，专利号：ZL9.8，授权日：2016.8.24
4. 李优鑫，包建民，赵璐萌，一种新型大通道电泳微芯片，发明专利，专利号：ZL9.5，授权日：2016.8.24
3. 包建民，续竞生，马志爽，张元津，李优鑫，一种样品制备仪，发明专利，专利号：1.5，授权日：2015.10.14
2. 包建民，李优鑫，贾菲菲，梁清刚，环糊精聚合物手性拆分剂的合成及应用，发明专利，专利号：ZL1.2，授权日：2014.10.1
1. 包建民，周正昌，李优鑫，带有磁力搅拌功能可控温型微反应器的自动进样托盘，发明专利，专利号：5.5，授权日：2013.8.14

Highlighted Publications
11. Futing Li, and Youxin Li*, Preparation of efficient and environment-friendly silica-supported EDTA platinum catalyst and its applications in hydrosilylation of olefins and methyldichlorosilane, Journal of Molecular Catalysis A: Chemical, 2016, 420: 254-263.
10. Yanfei Qi, Youxin Li*, and James J. Bao, Development of a capillary electrophoresis method for analyzing adenosine deaminase and purine nucleoside phosphorylase and its application in inhibitor screening, Analytical Biochemistry, 2016, 506: 31-44.
9.James J. Bao, Feifei Jia, Youxin Li*, Qinggang Liang, and Yan Wang, Synthesis and applications of sulfopropyl ether γ-cyclodextrin polymer as chiral selector in capillary electrophoresis, Analytical and Bioanalytical Chemistry, 2016, 408(13): 3639-3649.
8. Guanzhong Luo, Youxin Li*, and James J. Bao*, Development and application of a high-throughput sample cleanup process based on 96-well plate for simultaneous determination of 16 steroids in biological matrices using liquid chromatography-triple quadrupole mass spectrometry, Analytical and Bioanalytical Chemistry, 2016, 408(4): 1137-1149.
7. James J. Bao, Chaohui Sun, Youxin Li*, Ruijuan Yuan, Hui Xu, Guowen chen, and Shengyu Feng, A carbosilane dendrimer bonded silica as the stationary phase for capillary electrochromatography, Analytical Methods, 2015, 7(16): 6640-6646.
6. James J. Bao, Xiaojing Liu, Yong Zhang, and Youxin Li*, The development of a high-throughput measurement method of octanol/water distribution coefficient based on hollow fiber membrane solvent microextraction technique, Journal of Chromatography B, 2014, 967(15): 183-189.
5. Guirong Borijihan, Youxin Li*, Jianguo Gao, and James J. Bao*, Development of a novel 96-well format for liquid-liquid microextraction and its application in the HPLC analysis of biological samples, Journal of Separation Science, 2014, 37(9-10): 1155-1161.
4. Bo Zhang, Youxin Li, Henan Gao, Juan Bian, and James J. Bao*, Rapid determination of protein binding constant by a pressure-mediated affinity capillary electrophoresis method, Electrophoresis, 2011, 32(24): 3589-3596.
3. Youxin Li, Danning Liu, and James J. Bao*, Characterization of tyrosine kinase and screening enzyme inhibitor by capillary electrophoresis with laser-induced fluoresce detector, Journal of Chromatography B, 2011, 879(1): 107-112.
2. Youxin Li, Yongbo Dan, Xin Fang, and James J. Bao*, Preliminary studies of a novel multifunctional wide-bore electrophoresis system, Electrophoresis, 2010, 31(19): 3247-3255.
1. Youxin Li, Xin Fang, Shibin Zhao, Tingting Zhai, Xiaochun Sun, and James Jianmin Bao*, Study on a novel two-dimensional HPLC and wide-bore electrophoresis system, Chemistry Letters, 2010, 39(9): 983-985.

ResearcherID Publications
Year Title Author(s) Source Volume
2017 Design of hydrogels of 5-hydroxymethyl tolterodine and their studies on pharmacokinetics, pharmacodynamics and transdermal mechanism Liu, Wenhua; Teng, Lirong; Yu, Kongtong; et al. European Journal of Pharmaceutical Sciences 96
2017 Development of near zero-order release PLGA-based microspheres of a novel antipsychotic Zhao, Jinlong; Wang, Lexi; Fan, Chunyu; et al. International Journal of Pharmaceutics 516
2016 A novel prodrug strategy to improve the oral absorption of O-desmethylvenlafaxine Liu, Mingyuan; Sun, Yantong; Zhao, Sen; et al. Experimental and Therapeutic Medicine 12
2016 Application of hot-melt extrusion technology for designing an elementary osmotic pump system combined with solid dispersion for a novel poorly water-soluble antidepressant Zhang, Xuemei; Wang, Meng; Li, Pei; et al. Pharmaceutical Development and Technology 21
2016 Development and application of a high-throughput sample cleanup process based on 96-well plate for simultaneous determination of 16 steroids in biological matrices using liquid chromatography-triple quadrupole mass spectrometry Luo, G. Z.; Li, Y. X.; Bao, J. J. Analytical and Bioanalytical Chemistry 408
2016 Development and application of a high-throughput sample cleanup process based on 96-well plate for simultaneous determination of 16 steroids in biological matrices using liquid chromatography-triple quadrupole mass spectrometry Luo, Guanzhong; Li, Youxin; Bao, James J. Analytical and Bioanalytical Chemistry 408
2016 Development of a capillary electrophoresis method for analyzing adenosine deaminase and purine nucleoside phosphorylase and its application in inhibitor screening Qi, Y. F.; Li, Y. X.; Bao, J. J. Analytical Biochemistry 506
2016 Development of a capillary electrophoresis method for analyzing adenosine deaminase and purine nucleoside phosphorylase and its application in inhibitor screening Qi, Yanfei; Li, Youxin; Bao, James J. Analytical Biochemistry 506
2016 Enhanced delivery of Paclitaxel using electrostatically-conjugated Herceptin-bearing PEI/PLGA nanoparticles against HER-positive breast cancer cells Yu, Kongtong; Zhao, Jinlong; Zhang, Zunkai; et al. International Journal of Pharmaceutics 497
2016 Preparation of efficient and environment-friendly silica-supported EDTA platinum catalyst and its applications in hydrosilylation of olefins and methyldichlorosilane Li, F. T.; Li, Y. X. Journal of Molecular Catalysis a-Chemical 420