Yanjun Zhao ——Professor
Nationality:
CHINA

Phone:


Email:
zhaoyj@tju.edu.cn

Office:
Room 412-1, Building 24, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
J-6955-2012

Group weblink

http://faculty.tju.edu.cn/zhaoyj






Education Experience
2005-2010 Ph. D. Pharmacy King’s College London, UK
2002-2005 M.S. Biochemical Engineering Dalian Institute of Chemical Physics, CAS
1998-2002 Bachelor Polymer Dalian University of Technology

Professional Experience
2009-2009 Research Scientist MedPharm Ltd. (UK)
2010-2012 Lecturer Tianjin University, China
2012-2018 Associate Professor Tianjin University, China
2018- Professor Tianjin University, China

Research Area
The research in the group of Zhao encompasses four main areas, including (1) Stimuli-responsive drug delivery systems; (2) Ferroptosis-targeting nanomedicines; (3) Photo-triggered microtubule inhibitors; (4) Pharmaceutical micelles, biomaterials and nanomaterials.



Honors and Awards
2013: Tianjin University “Elite Scholar”
2009: Chinese Government Award for Outstanding Self-financed Students Abroad
2005: Dorothy Hodgkin Postgraduate Awards

Patents
CN Patent: ZL 2013 1 **.7
CN Patent: ZL 2014 1 **.9
CN Patent: ZL 2016 1 **.7
CN Patent: ZL 2016 1 **.7

Highlighted Publications
Zhu J, Dai P, Liu F, Li Y, Qin Y, Yang Q, Tian R, Fan A, Medeiros SF, Wang Z, Zhao Y, 2020. Upconverting nanocarriers enable triggered microtubule inhibition and concurrent ferroptosis induction for selective treatment of triple-negative breast cancer. Nano Lett., in press (doi: 10.1021/acs.nanolett.0c00502).
Meng X, Deng J, Liu F, Guo T, Liu M, Dai P, Fan A, Wang Z, Zhao Y, 2019. Triggered all-active metal organic framework: ferroptosis machinery contributes to the apoptotic photodynamic antitumor therapy. Nano Lett., 19(11):7866-7876.
Gao M, Deng J, Liu F, Fan A, Wang Y, Wu H, Ding D, Kong D, Wang Z, Peer D, Zhao Y, 2019. Triggered ferroptotic polymer micelles for reversing multidrug resistance to chemotherapy. Biomaterials, 223: 119486.
Meng X, Gao M, Deng J, Lu D, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Self-immolative micellar drug delivery: the linker matters. Nano Res, 2018, 11(12), 6177–6189.
Gao M, Meng X, Guo X, Zhu J, Fan A, Wang Z, Zhao Y. All-active anti-tumor micelles via triggered lipid peroxidation. J Control Release, 2018, 286: 381-393.
Li X, Gao M, Xin K, Zhang L, Ding D, Kong D, Wang Z, Shi Y, Kiessling F, Lammers T, Cheng J, Zhao Y. Singlet oxygen-responsive micelles for enhanced photodynamic therapy. J Control Release. 2017, 260:12-21.

ResearcherID Publications
Year Title Author(s) Source Volume
2013 The effect of solute-membrane interaction on solute permeation under supersaturated conditions Zhang, Jingsi; Sun, Mingjing; Fan, Aiping; et al. International Journal of Pharmaceutics 441
2013 The dominant role of polymer erosion in paclitaxel release from folate-modified poly(ether-anhydride) nanocarrier Liu, Xipan; Pan, Dan; Guo, Qian; et al. Journal of Applied Polymer Science 129
2013 Hydroxylamine amplified gold nanoparticle-based aptameric system for the highly selective and sensitive detection of platelet-derived growth factor Wang, Ping; Song, Yinhuan; Zhao, Yanjun; et al. Talanta 103
2013 Engineering magnetic-molecular sequential targeting nanoparticles for anti-cancer therapy Zhang, Qi; Zhu, Jundong; Song, Lichao; et al. Journal of Materials Chemistry B
2013 Comparison of four-arm and six-arm star-shaped mPEG-PLA block copolymer micelles for drug delivery Zhao, Yanjun; Pan, Dan; Wang, Zheng Journal of Controlled Release 172
2014 Two birds with one stone: dendrimer surface engineering enables tunable periphery hydrophobicity and rapid endosomal escape Wang, Zheng; Chen, Chao; Liu, Ruihong; et al. Chemical Communications
2014 Turn-on chemiluminescent sensing platform for label-free protease detection using streptavidin-modified magnetic beads Zhang, Huanhuan; Yu, Dalong; Zhao, Yanjun; et al. Biosensors and Bioelectronics 61
2014 Tailored dual coating of magnetic nanoparticles for enhanced drug loading Song, Lichao; Sun, Mingjing; Zhao, Yanjun; et al. RSC Advances 4
2014 Modulating topical drug delivery via skin pre-treatment with low-generation poly(amidoamine) dendrimers Guo, Chenchen; Zhang, Yu; Sun, Mingjing; et al. Journal of Drug Delivery Science and Technology 24
2014 Modifying theophylline microparticle surfaces via the sequential deposition of poly(vinyl alcohol-co-vinyl acetate) copolymers Zhao, Yanjun; Alas’ad, Mannar A.; Jones, Stuart A. International Journal of Pharmaceutics 463