Jianyong Zhang——Associate Professor
Nationality:
CANADA

Phone:


Email:
Jianyong.zhang@tju.edu.cn

Office:
Room 506, Building 24, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
L-5934-2015

Group weblink








Education Experience
2007 Postdoctoral McGill University, Canada
2007 Ph. D. University of Tsukuba, Japan

Professional Experience
2014-2015 Assosiate Professor Tianjin University, China
2007-2011 Postdoctoral McGill University, Canada
2001-2007 Teaching Assistant University of Tsukuba, Japan
1992-2000 Physician and Physician-in-charge Tianjin 4th Central Hospital, China

Research Area
The research in the group of ZHANG focuses on two areas: 1) Mechanisms of transcriptional regulation involved in cancer，oxidative stress response and a variety of health disorders by means of molecular biology method, 2) Mechanism study on interaction of host factors with retroelements and HIV-1 such as helicases, interferon-stimulate genes and RNA binding proteins etc.



Honors and Awards
Best Teacher Award, Tianjin 4th central hospital, 1994
Best Teacher Award, Tianjin 4th central hospital, 1995

Patents


Highlighted Publications
Li, Xiaoyu#; Zhang, Jianyong#; Jia, Rui; et al. The MOV10 Helicase Inhibits LINE-1 Mobility.（#Co- first author) Journal of Biological Chemistry Volume: 288 Issue: 29 Pages: 21148-21160 Published: JUL 19 2013
Zhang, Jianyong; Liang, Chen. BST-2 Diminishes HIV-1 Infectivity. Journal of Virology Volume: 84 Issue: 23 Pages: 12336-12343 Published: DEC 2010
Rong, Liwei; Zhang, Jianyong; Lu, Jennifer; et al. The Transmembrane Domain of BST-2 Determines Its Sensitivity to Down-Modulation by Human Immunodeficiency Virus Type 1 Vpu. Journal of Virology Volume: 83 Published: DEC 2009
Zhang, Jianyong; Hosoya, Tomonori; Maruyama, Atsushi; et al. Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes. Biochemical Journal 15;404(3):459-66, Jun 2007
Zhang, Jianyong; Ohta, Tsutomu; Maruyama, Atsushi; et al. BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress.Molecular and Cellular Biology Volume: 26 Issue: 21 Pages: 7942-7952 Published: NOV 2006

ResearcherID Publications
Year Title Author(s) Source Volume
2013 The MOV10 Helicase Inhibits LINE-1 Mobility Li, Xiaoyu; Zhang, Jianyong; Jia, Rui; et al. Journal of Biological Chemistry 288
2010 BST-2 Diminishes HIV-1 Infectivity Zhang, Jianyong; Liang, Chen Journal of Virology 84
2009 Insulin-like growth factor II mRNA binding protein 1 modulates Rev-dependent human immunodeficiency virus type 1 RNA expression Zhou, Yongdong; Rong, Liwei; Zhang, Jianyong; et al. Virology 393
2009 Mechanistic study of BST-2 down-modulation by HIV-1 Vpu Zhang, Jianyong; Rong, Liwei; Wainberg, Mark A.; et al. Retrovirology 6
2009 The Transmembrane Domain of BST-2 Determines Its Sensitivity to Down-Modulation by Human Immunodeficiency Virus Type 1 Vpu Rong, Liwei; Zhang, Jianyong; Lu, Jennifer; et al. Journal of Virology 83
2007 BRG1 and actin-related motif in Nrf2 is essential for Nrf2-mediated heme oxygenase 1 induction Itoh, K.; Zhang, J.; Maruyama, A.; et al. Febs Journal 274
2007 Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of maf homodimer Kimura, Momoko; Yamamoto, Tae; Zhang, Jianyong; et al. Journal of Biological Chemistry 282
2007 Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes Zhang, Jianyong; Hosoya, Tomonori; Maruyama, Atsushi; et al. Biochemical Journal 404
2006 BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress Zhang, Jianyong; Ohta, Tsutomu; Maruyama, Atsushi; et al. Molecular and Cellular Biology 26