Kang Zhao——Professor
Nationality:
USA

Phone:


Email:
kangzhao@tju.edu.cn

Office:
Room 453, Building 11, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
K-3777-2015

Group weblink








Education Experience
1988 Ph. D. Columbia University, NY, USA
1988 Postdoctoral Columbia University, NY, USA

Professional Experience
2001-2015 Professor Tianjin University
2001-2003 Dean Tianjin University
2001-2003 Director TEDA, Tianjin
1995-1999 Professor W. M. Keck Foundation Early
1990-1992 Fellow Columbia Univ

Research Area
The research in the group of Zhao is encompassed in 4 main areas, including 1) Medicinal Chemistry: Design and synthesis of drug molecules, and development of synthetic route to drug intermediates, 2) Biological Organic Chemistry: Investigation of anti-cocaine, monoclonal antibodies, and anti-viruses, 3) Organic Synthetic Methodology: Hypervalent iodine chemistry and heterocyclic chemistry, and 4) Total Synthesis of Complex Molecules: design and synthesis of natural products.



Honors and Awards
杜云飞，四乙酰核糖和二乙酰阿昔洛韦合成的新工艺，天津市人民政府，科技进步奖，二等奖，2010。（赵康、陈维瑜、魏静、杜云飞、王松青、苏艳芳、张秀东、陈炎泉）

Patents
杜云飞，马辉，赵康，异吲哚啉羧酸酯衍生物的制备方法及其应用，中国，8.1。
杜云飞，汤丽娜，庞永乐，阎俏，祁秀香，一种合成Coumestan类衍生物的新方 法，中国，9.0。
祁秀香，杜云飞，闫俏，赵康，李慧，合成N-芳基吲哚-3-腈衍生物的方法，中 国，3.2。
杜云飞，云希柳，毕文英，赵康，一种氮取代四氢咔唑酮衍生物的制备新方法 ，中国，3.0。
杜云飞，赵康，赵菲菲，刘昕，齐蕊，2-三氟甲基噁唑类衍生物的合成方法， 中国，8.7。
杜云飞，刘乐，贺巧巧，赵康，1,3-二腈基2-取代-1H-茚类衍生物及其制备方 法，中国，9.1。
杜云飞，吕晶磊，尚巳耘，赵康，一种四氢-γ-咔啉类衍生物的合成方法，中 国，8.4。
杜云飞，李旭明，张翔，赵康，一种二苯西平类衍生物的合成方法，中国，2.1。
杜云飞，吕晶磊，赵康，一种2-吲哚酮-3-羧酸酯类衍生物的合成方法，中国，2 .2。
杜云飞，尚巳耘，赵康，一种合成二苯并二氢-1,3-二氮杂?类衍生物的方法， 中国，4.8。
杜云飞，程然，赵康，一种通过环合消除一锅法合成4（3H）-喹唑啉酮衍生物的 方法，中国，5.0。
杜云飞，程然，赵康，一种通过环合消除一锅法合成4（3H）-喹唑啉酮衍生物的 方法，中国，5.0。
杜云飞，袁玉成，赵康，一种通过C–N氧化偶联合成取代二氨基烯烃衍生物的方 法，中国，20**

Highlighted Publications
Shang, S.; Zhang-Negrerie, D.; Du, Y.; Zhao, K. Intramolecular Metal-free Oxidative Aryl-aryl Coupling: An Unusual Hypervalent Iodine-mediated Rearrangement of 2-Substituted N-Phenylbenzamides. Angew. Chem., Int. Ed. 2014, 53, 6216 (Hot Paper).
Liu, L.; Lu, H.; Wang, H.; Yang, C.; Zhang, X.; Zhang-Negrerie, D.; Du, Y.; Zhao, K. PhI(OCOCF3)2-Mediated C-C Bond Formation Concomitant with a 1,2-Aryl Shift in a Metal-Free Synthesis of 3-Arylquinolin-2-ones. Org. Lett. 2013, 15, 2906.
Du, Y.-F.; Liu, R.-H.; Linn, G.; Zhao, K. Synthesis of N-Substituted Indole Derivatives via PIFA-Mediated Intramolecular Cyclization. Org. Lett. 2006, 8, 5919.
Landry, D. W.; Zhao, K.; Yang, G. X. Q.; Glickman, M; Georgiadis, T. M. Antibody-Catalyzed Degradation of Cocaine. Science 1993, 259, 1899.
Stork, G.; Zhao, K. Total Synthesis of (-)-Histrionicotoxin and (-)-Histrionicotoxin 235A. J. Am. Chem. Soc. 1990, 112, 5875.

ResearcherID Publications
Year Title Author(s) Source Volume
1989 A SIMPLE METHOD OF DETHIOACETALIZATION STORK, G; ZHAO, K Tetrahedron Letters 30
1989 A STEREOSELECTIVE SYNTHESIS OF (Z)-1-IODO-1-ALKENES STORK, G; ZHAO, K Tetrahedron Letters 30
1990 TOTAL SYNTHESES OF (-)-HISTRIONICOTOXIN AND (-)-HISTRIONICOTOXIN-235A STORK, G; ZHAO, K Journal of the American Chemical Society 112
1990 THE ALLYLIC EPOXIDE CYCLIZATION - A METHOD FOR THE CONTROL OF REGIOCHEMISTRY AND STEREOCHEMISTRY IN CYCLOHEXANE SYSTEMS STORK, G; KOBAYASHI, Y; SUZUKI, T; et al. Journal of the American Chemical Society 112
1993 TETRAZOLE CATALYZED SYNTHESIS OF PHOSPHONATE ESTERS ZHAO, K; LANDRY, DW Tetrahedron 49
1993 ANTIBODY-CATALYZED DEGRADATION OF COCAINE LANDRY, DW; ZHAO, K; YANG, GXQ; et al. Science 259
1994 STABILIZATION OF GLYCOSYL SULFONIUM IONS FOR STEREOSELECTIVE O-GLYCOSYLATION SUN, LH; LI, P; ZHAO, K Tetrahedron Letters 35
1994 PREPARATION AND USE OF 1-IODOALKYL YLIDES CHEN, J; WANG, T; ZHAO, K Tetrahedron Letters 35
1995 SYNTHESIS OF 1-THIOGLYCOSIDES LI, P; SUN, LH; LANDRY, DW; et al. Carbohydrate Research 275
1995 A REGIOCONTROLLED INTRAMOLECULAR O-CYCLIZATION WANG, T; HONG, F; ZHAO, K Tetrahedron Letters 36