摘要/Abstract

高价有机碘化合物的反应性质与过渡金属相似, 其参与的反应具有反应条件较温和、选择性好、产率高及环境友好等优点, 因而近年来关于高价有机碘试剂的研究受到广泛关注, 在有机合成领域中获得了较多应用. 综述了近年来高价有机碘试剂2-碘酰基苯基酸(IBX)在有机合成中的研究及应用, 包括IBX在氧化羟基、含氮化合物和含硫化合物, 在制备αβ-不饱和羰基化合物和α,β-不饱和酯, 以及在不对称合成等方面的应用. 最后介绍了近期对IBX的改进.
关键词: 2-碘酰基苯甲酸(IBX), 氧化, 有机合成, 高价有机碘
High-valent organoiodine reagents have many reaction characteristics similar to transition metals, and high-valent organoiodine-mediated reactions feature mild reaction conditions, good product selectivity, high yield and environmental friendliness. Therefore, they have been widely studied and applied in organic synthesis. The recent research progress of 2-iodoxybenzoic acid in organic synthesis is reviewed, including the oxidation of hydroxyl group, nitrogen-containing compounds and sulfur-containing compounds, the preparation of α,β-unsaturated carbonyl compounds and esters, and the application in asymmetric synthesis. The recent improvement of IBX is also introduced.
Key words: 2-iodoxybenzoic acid (IBX), oxidation, organic synthesis, high-valent organoiodine


PDF全文下载地址:

点我下载PDF