摘要/Abstract
以廉价的卤化钾为卤源，Oxone为氧化剂，一系列烯丙胺在温和的条件下经过卤环化反应以较好的产率得到5-卤甲基-2-噁唑啉.该方法的优势在于应用了便宜的卤源，没有有机副产物的产生，具有成本低廉和环保友好的特点.5-卤甲基-2-噁唑啉还可以通过不同的亲核取代反应得到许多有用的衍生物.
关键词: Oxone, 卤环化, 噁唑啉
With inexpensive potassium halide (KX) as halogen source, and oxone as oxidant, a series of allylamides underwent halocyclization reaction and generated 5-halomethyl-2-oxazolines in good to excellent isolated yields under mild conditions. The protocol showed attractive advanced features including low cost of halogen source, absence of organic byproduct, and resultant environmental-friendly nature. In addition, various useful derivatives could be expected by proper nucleophilic substitution reactions.
Key words: oxone, halocyclization, oxazolines
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