摘要/Abstract

有机碱催化不对称合成是小分子催化化学的重要分支，也是手性合成领域的研究热点之一.膦腈碱化合物是有机超强碱，性质稳定，可作为一类有机强碱小分子催化剂应用于不对称催化有机反应.讨论了膦腈碱化合物在小分子催化领域的研究进展，包括膦腈碱的合成以及其在不对称反应中的应用.
关键词: 手性膦腈碱, 不对称, 研究进展, 有机催化
As organocatalysts, organic base catalysts play an important role in the quest for optically pure compounds. Chiral iminophosphoranes, being organosuperbases, are very stable under air and moisture conditions, thereby providing an attractive platform for the design of various asymmetric organocatalysts. The recent achievements concerning chiral iminophosphoranes in the development of both organocatalysis and their applications in asymmetric synthesis are summarized and discussed.
Key words: chiral iminophosphorane, asymmetric catalysis, research progress, organocatalysis


PDF全文下载地址:

点我下载PDF