摘要/Abstract

十二顶点碳硼烷是一类含有碳、氢及硼原子的簇合物，具有特殊的热稳定性和化学稳定性，在医药、材料、能源、配位化学及金属有机化学中都得到广泛的应用.因此，其官能团化成为该领域的研究热点.其中过渡金属介导/催化的多组分串联反应不仅具有高原子经济性的特点，还可以通过简单的原料和简便的操作，不经中间产物分离，以高选择性直接获取复杂产物.总结了近年来过渡金属参与的十二顶点碳硼烷C，C-、C，B-或B，B-顶点通过多组分串联反应高效官能团化的研究进展，同时对部分反应机理进行了讨论，并就该研究领域所面临的挑战和发展前景进行了展望.
关键词: 硼烷簇合物, 碳硼烷, 过渡金属, 官能团化, 串联反应
Carboranes are a class of carbon-boron molecular clusters with exceptional thermal and chemical stabilities. They are finding a variety of applications in medicine, materials, and coordination/organometallic chemistry as functional building blocks. To this end, the selective functionalization of carboranes has received growing research interests. Transition metal-promoted multicomponent cascade reactions are particularly attractive since they have the advantages of step- and atom- economy for the construction of complex products from readily available starting materials by simple operations. The recent advances in transition metal-promoted multicomponent cascade reactions for selective functionalization of carboranes are summarized in this focus review. The related reaction mechanisms and challenges in this research area are also discussed.
Key words: borane cluster, carborane, transition metal, functionalization, cascade reaction


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