摘要/Abstract

硒（Se）在生命体内是一种重要的微量元素，含有硒的蛋白质在哺乳动物体内具有广泛的生物学效应，如抗氧化、抗炎和促进产生甲状腺激素等作用.在过去的几十年里，含硒物质因其在生物体内的生物活性而引起人们的极大关注，其主要归因于Se元素的氧化还原及软硬质子性能.近年来，随着荧光检测技术的发展，大量硒化合物荧光传感器被开发出来.主要综述了含硒物质如硒代半胱氨酸（Sec）、硒化氢、硒醇和Se（IV）等荧光传感器的研究进展，并对其研究前景进行了展望.
关键词: 硒化合物, 荧光传感器, 生物成像, 荧光检测, 纳米颗粒
Selenium (Se) is an important trace element in life and has been associated with many diseases. Protein containing selenium has a wide range of biological effects, such as antioxidant, anti-inflammatory and promotes the production of thyroid hormone action. In the past few decades, selenium has attracted great attention because of its important role in biology, which is mainly attributed to the redox of Se elements and the properties of hard and soft protons. In recent years, with the development of chemical simulation technology, a large number of selenium-related fluorescent chemosensors have been developed to monitor physiological and pathological processes. Fluorescent chemosensors containing selenium materials, such as selenocysteine (Sec), hydrogen selenide and Se(IV) are reviewed. The development tendency of the sensing Se compounds is prospected.
Key words: Se compound, fluorescent sensor, bioimaging, fluorescent detection, nanoparticle


PDF全文下载地址:

点我下载PDF