摘要/Abstract
报道了一种新型的由二芳基二硫醚和醇双亚磺酰化反应来制备亚磺酸酯的方法.在Selectfluor作为氧化剂的条件下，一分子二硫醚与两分子醇反应，能够顺利转化得到两分子亚磺酸酯产物.该反应无需金属催化剂，在简单温和的条件下即可进行，反应产率很高.反应底物适用性广，含有不同取代基的二硫醚和醇，包括天然的手性醇类化合物，均能很好地发生反应得到相应的产物.该方法实现了简单条件下通过醇的亚磺酰化反应高效地构建亚磺酸酯，为亚磺酸酯及其衍生物的合成提供了一条新的途径.
关键词: Selectfluor, 二硫醚, 亚磺酰化, 亚磺酸酯, C—O键断裂
An oxidative twofold sulfination of alcohol with Selectfluor as an efficient oxidant was developed. This reaction proceeded smoothly achieving the unprecedented sulfination transformation of varieties of diaryldisulfides and alcohols under simple conditions, affording the corresponding sulfinic esters in excellent yields. The current reaction provides a new and convenient strategy for the preparation of sulfinic esters.
Key words: Selectfluor, disulfide, sufination, sulfinic ester, C-O bond cleavage
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