摘要/Abstract

N-氟代二苯磺酰亚胺（NFSI）的胺化反应已成为制备胺类化合物的重要方法，但利用它制备N-烯基磺酰亚胺的方法不多.在磷酸氢二钠存在下，碳酸银和1，10-菲啰啉衍生物共同催化NFSI与丙炔酸酯或丙炔酰胺发生氢胺化反应，高选择性地生成顺式N-烯基二苯磺酰亚胺类化合物，产率为35%～71%.
关键词: 碳酸银, N-氟代二苯磺酰亚胺, N-烯基二苯磺酰亚胺, 丙炔酸酯, 丙炔酰胺
Amination using N-fluorobenzenesulfonimide (NFSI) as nitrogen source has become an important route to prepare amines. However, there are few methods to prepare N-vinyl sulfonimides using NFSI as nitrogen source. In the presence of Na₂HPO₄, the hydroamination of propiolates or propiolamides with N-fluorobenzenesulfonimide (NFSI) was realized, where Ag₂CO₃ and 1,10-phenanthroline derivatives were added as catalysts. It leads to N-vinyldibenzenesulfonimides in high selectivity of Z isomers in the yields of 35%~71%.
Key words: silver carbonate, N-fluorobenzenesulfonimide, N-vinyldibenzenesulfonimide, propiolate, propiolamide


PDF全文下载地址:

点我下载PDF