摘要/Abstract

在氮杂环卡宾（NHC）催化下，查尔酮衍生物与α-溴代烯醛经过"Michael加成-Michael加成-内酯化"等串联过程，一步合成了官能化萘并吡喃酮.该方法具有产率高、底物易得和条件温和等优点，为萘并吡喃酮的高效构建和官能化提供了新思路.
关键词: 氮杂环卡宾(NHC), α-溴代烯醛, 查尔酮衍生物, 官能化萘并吡喃酮, 串联反应
An efficient N-heterocyclic carbene (NHC)-catalyzed "Michael-Michael-Lactonization" cascade process involving chalcone derivatives and α-bromoenals for the syntheses of functionalized naphthopyranones was disclosed. This approach was qualified with good yields, readily available starting materials and mild reaction conditions.
Key words: N-heterocyclic carbene (NHC), α-bromoenals, chalcone derivatives, functionalized naphthopyranone, cascade reaction


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