摘要/Abstract

开发了一种基于协同效应的新型肼荧光探针.通过在发色团上引入两种不同的识别位点，双识别位点的协同效应使得该探针对肼具有良好的专一性和灵敏度，检测限可达0.05~10.0μmol·L^-1.此外，该探针还可用于细胞（Bt-474）中肼的检测.
关键词: 水合肼, 协同效应, 细胞成像, 荧光探针
Hydrazine is an important raw material and catalyst in chemical industry. However, hydrazine is very harmful to human organs. A new type of probe was developed based on the synergistic effect. Two recognition sites were introduced into the probe to improve performance to hydrazine, which has good specificity to hydrazine. The limit of detection (LOD) for N₂H₄ was 0.05~10.0 μmol·L^-1. Moreover, the probe could detect N₂H₄ in BT-474 cells.
Key words: hydrazine, synergistic effect, cell imaging, fluorescent probe


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